Literature DB >> 11779470

A genetic basis for obsessive grooming.

Ann M Graybiel1, Esen Saka.   

Abstract

Excessive grooming behaviors, cleansing rituals, and self-mutilation are important features of a range of neuropsychiatric diseases including obsessive compulsive (OC)-spectrum disorders. In this issue of Neuron, Greer and Capecchi (2002) report that Hoxb8 mutant mice exhibit this behavioral phenotype. These Hoxb8 mutants will be valuable in exploring the genetics and pathophysiology of OC-spectrum disorders as well as strategies for their treatment.

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Year:  2002        PMID： 11779470     DOI： 10.1016/s0896-6273(01)00575-x

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  7 in total

Review 1.  The thalamus as a monitor of motor outputs.

Authors:  R W Guillery; S M Sherman
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2002-12-29       Impact factor: 6.237

Review 2.  The role of the thalamus in the flow of information to the cortex.

Authors:  S Murray Sherman; R W Guillery
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2002-12-29       Impact factor: 6.237

Review 3.  Altered trajectories of neurodevelopment and behavior in mouse models of Rett syndrome.

Authors:  Elizabeth S Smith; Dani R Smith; Charlotte Eyring; Maria Braileanu; Karen S Smith-Connor; Yew Ei Tan; Amanda Y Fowler; Gloria E Hoffman; Michael V Johnston; Sujatha Kannan; Mary E Blue
Journal:  Neurobiol Learn Mem       Date:  2018-11-29       Impact factor: 2.877

Review 4.  Refining psychiatric genetics: from 'mouse psychiatry' to understanding complex human disorders.

Authors:  Justin L Laporte; Renee F Ren-Patterson; Dennis L Murphy; Allan V Kalueff
Journal:  Behav Pharmacol       Date:  2008-09       Impact factor: 2.293

Review 5.  Roles of micro-opioid receptors in GABAergic synaptic transmission in the striosome and matrix compartments of the striatum.

Authors:  Masami Miura; Masao Masuda; Toshihiko Aosaki
Journal:  Mol Neurobiol       Date:  2008-05-13       Impact factor: 5.590

Review 6.  Neurobiology of rodent self-grooming and its value for translational neuroscience.

Authors:  Allan V Kalueff; Adam Michael Stewart; Cai Song; Kent C Berridge; Ann M Graybiel; John C Fentress
Journal:  Nat Rev Neurosci       Date:  2015-12-17       Impact factor: 34.870

7.  Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: a model of obsessive compulsive disorder and Tourette's.

Authors:  Kent C Berridge; J Wayne Aldridge; Kimberly R Houchard; Xiaoxi Zhuang
Journal:  BMC Biol       Date:  2005-02-14       Impact factor: 7.431
  7 in total

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