| Literature DB >> 11779459 |
Abstract
Surface and secreted proteins are synthesized in the endoplasmic reticulum where they must fold and assemble before being transported. Changes in the ER that interfere with their proper maturation initiate the unfolded protein response pathway. New studies have filled in a missing link between the yeast and mammalian pathways.Entities:
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Year: 2001 PMID: 11779459 DOI: 10.1016/s0092-8674(01)00623-7
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582