| Literature DB >> 117788 |
Abstract
Incorporation of 14C-thymidine by cells infected with African swine fever virus (ASFV) occurs in the nucleus. Part of this DNA is transferred to the cytoplasm and becomes resistant to DNAse. The nuclear fraction washed with Triton X100 retained all labeled DNA and was able to synthesize viral and cellular DNA under in vitro conditions in the presence of the four deoxynucleoside triphosphates, Mg+2, and sucrose. Under similar conditions nuclei from uninfected cells synthesized very little DNA.Entities:
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Year: 1979 PMID: 117788 DOI: 10.1007/bf01320591
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574