Literature DB >> 11778422

Psychological casualties resulting from chemical and biological weapons.

J A Romano1, J M King.   

Abstract

This symposium addresses the complications encountered by medical planners when confronted by the use or threat of the use of weapons of mass destruction. The types of chemical warfare agents (CWA), their principal target organs, and physiological effects are discussed. We have reviewed the use of CWA in 20th century warfare and otherwise with emphasis on five cases: (1) use of sulfur mustard during World War I; (2) use by Italy against Ethiopia; (3) use in the Sino-Japanese War; (4) relatively well-studied use in the Iran-Iraq conflict; and (5) the use of sarin in the Tokyo subway terrorist incident. We reviewed the additional physiological and psychological consequences of their use and threat of use. Results from training and simulation are discussed. Finally, we present our conclusions derived from the analysis of these historical situations.

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Year:  2001        PMID: 11778422

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  12 in total

1.  Prehospital management and medical intervention after a chemical attack.

Authors:  L Kenar; T Karayilanoglu
Journal:  Emerg Med J       Date:  2004-01       Impact factor: 2.740

2.  Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.

Authors:  Edson X Albuquerque; Edna F R Pereira; Yasco Aracava; William P Fawcett; Maristela Oliveira; William R Randall; Tracey A Hamilton; Robert K Kan; James A Romano; Michael Adler
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-16       Impact factor: 11.205

3.  Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds.

Authors:  Edna F R Pereira; Yasco Aracava; Louis J DeTolla; E Jeffrey Beecham; G William Basinger; Edgar J Wakayama; Edson X Albuquerque
Journal:  J Pharmacol Exp Ther       Date:  2014-06-06       Impact factor: 4.030

4.  Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance.

Authors:  Jacek Mamczarz; Girish S Kulkarni; Edna F R Pereira; Edson X Albuquerque
Journal:  Neurotoxicology       Date:  2011-07-19       Impact factor: 4.294

5.  Acute toxicity of organophosphorus compounds in guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition.

Authors:  William P Fawcett; Yasco Aracava; Michael Adler; Edna F R Pereira; Edson X Albuquerque
Journal:  J Pharmacol Exp Ther       Date:  2008-11-04       Impact factor: 4.030

6.  An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint.

Authors:  Jacek Mamczarz; Edna F R Pereira; Yasco Aracava; Michael Adler; Edson X Albuquerque
Journal:  Neurotoxicology       Date:  2009-10-31       Impact factor: 4.294

7.  The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice.

Authors:  Fabio Pibiri; Alan P Kozikowski; Graziano Pinna; James Auta; Bashkim Kadriu; Erminio Costa; Alessandro Guidotti
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-10       Impact factor: 11.205

8.  Oral Pretreatment with Galantamine Effectively Mitigates the Acute Toxicity of a Supralethal Dose of Soman in Cynomolgus Monkeys Posttreated with Conventional Antidotes.

Authors:  Malcolm Lane; D'Arice Carter; Joseph D Pescrille; Yasco Aracava; William P Fawcett; G William Basinger; Edna F R Pereira; Edson X Albuquerque
Journal:  J Pharmacol Exp Ther       Date:  2020-08-05       Impact factor: 4.030

9.  Molecular and cellular actions of galantamine: clinical implications for treatment of organophosphorus poisoning.

Authors:  Edna F R Pereira; Yasco Aracava; Manickavasagom Alkondon; Miriam Akkerman; Istvan Merchenthaler; Edson X Albuquerque
Journal:  J Mol Neurosci       Date:  2009-08-19       Impact factor: 3.444

10.  Effectiveness of donepezil, rivastigmine, and (+/-)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamine.

Authors:  Yasco Aracava; Edna F R Pereira; Miriam Akkerman; Michael Adler; Edson X Albuquerque
Journal:  J Pharmacol Exp Ther       Date:  2009-09-09       Impact factor: 4.030

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