Literature DB >> 11776387

Single-nucleotide polymorphisms of the proprotein convertase subtilisin/ kexin type 5 (PCSK5) gene.

H Cao1, A Mok, B Miskie, R A Hegele.   

Abstract

The proprotein convertase. subtilisin/kexin type 5, or PCSK5, mediates post-translational endoproteolytic processing for several integrin alpha subunits. We identified two silent single-nucleotide polymorphisms (SNPs) in PCSK5, which were found to vary in frequency across ethnic groups. The identification of these amplification primers and SNPs provides tools to investigate PCSK5 for association with inflammatory or vascular phenotypes.

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Year:  2001        PMID: 11776387     DOI: 10.1007/s100380170008

Source DB:  PubMed          Journal:  J Hum Genet        ISSN: 1434-5161            Impact factor:   3.172


  6 in total

1.  A genome-wide search for linkage to chronic kidney disease in a community-based sample: the SAFHS.

Authors:  Nedal H Arar; Venkata S Voruganti; Subrata D Nath; Farook Thameem; Richard Bauer; Shelley A Cole; John Blangero; Jean W MacCluer; Anthony G Comuzzie; Hanna E Abboud
Journal:  Nephrol Dial Transplant       Date:  2008-04-28       Impact factor: 5.992

2.  Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels.

Authors:  Iulia Iatan; Zari Dastani; Ron Do; Daphna Weissglas-Volkov; Isabelle Ruel; Jenny C Lee; Adriana Huertas-Vazquez; Marja-Riitta Taskinen; Annik Prat; Nabil G Seidah; Päivi Pajukanta; James C Engert; Jacques Genest
Journal:  Circ Cardiovasc Genet       Date:  2009-08-22

Review 3.  Personalized Medicine: New Perspectives for the Diagnosis and the Treatment of Renal Diseases.

Authors:  Anna Gluba-Brzózka; Beata Franczyk; Robert Olszewski; Maciej Banach; Jacek Rysz
Journal:  Int J Mol Sci       Date:  2017-06-10       Impact factor: 5.923

4.  Discovery of core genes in colorectal cancer by weighted gene co-expression network analysis.

Authors:  Cun Liao; Xue Huang; Yizhen Gong; Qiuning Lin
Journal:  Oncol Lett       Date:  2019-07-11       Impact factor: 2.967

5.  Identification of Estrogen Signaling in a Prioritization Study of Intraocular Pressure-Associated Genes.

Authors:  Hannah A Youngblood; Emily Parker; Jingwen Cai; Kristin Perkumas; Hongfang Yu; Jason Sun; Sylvia B Smith; Kathryn E Bollinger; Janey L Wiggs; Louis R Pasquale; Michael A Hauser; W Daniel Stamer; Yutao Liu
Journal:  Int J Mol Sci       Date:  2021-09-24       Impact factor: 6.208

6.  Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.

Authors:  Astrid Rohrbeck; Jürgen Borlak
Journal:  PLoS One       Date:  2009-10-08       Impact factor: 3.240

  6 in total

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