L Zhou1, G Du. 1. Department of Neurosurgery, Huashan Hospital, Shanghai Medical University, Shanghai 200040, China. lfzhou@shmu.edu.cn
Abstract
OBJECTIVE: To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangioblastomas (PFSHs). METHODS: The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retrospectively and a review of relevant literature was conducted. RESULTS: The preoperative definitive diagnosis rate was 13/22. Total tumor removal was achieved in 20 patients. Two of the 22 patients died after surgery, one of brain-stem injury and the other from an intracranial hemorrhage. Twenty patients were followed up for 2 months to 8 years (average, 2 years). Kamofsky scale was > or = 80 in 15 patients, 60-70 in 1 patient and not measured in 4 patients who died during follow-up. The causes of death were pneumonia (2 patients) and purulent meningitis (2). CONCLUSION: MRI and DSA (digital subtraction angiography) are major preoperative diagnostic modalities for PFSH, but PFSH remains a challenging benign neoplasm. Special microsurgical techniques and improved operative manipulation can improve surgical efficacy.
OBJECTIVE: To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangioblastomas (PFSHs). METHODS: The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retrospectively and a review of relevant literature was conducted. RESULTS: The preoperative definitive diagnosis rate was 13/22. Total tumor removal was achieved in 20 patients. Two of the 22 patients died after surgery, one of brain-stem injury and the other from an intracranial hemorrhage. Twenty patients were followed up for 2 months to 8 years (average, 2 years). Kamofsky scale was > or = 80 in 15 patients, 60-70 in 1 patient and not measured in 4 patients who died during follow-up. The causes of death were pneumonia (2 patients) and purulent meningitis (2). CONCLUSION: MRI and DSA (digital subtraction angiography) are major preoperative diagnostic modalities for PFSH, but PFSH remains a challenging benign neoplasm. Special microsurgical techniques and improved operative manipulation can improve surgical efficacy.
Authors: Javier Ros de San Pedro; Fernando Alarcón Rodríguez; Belén Ferri Níguez; Juan F Martínez-Lage Sánchez; Antonio López López-Guerrero; Matías Felipe Murcia; Antonio M Ruíz-Espejo Vilar Journal: Neurosurg Rev Date: 2010-01 Impact factor: 3.042