Literature DB >> 11774089

Use of rabies vaccines after reconstitution and storage.

Pakamatz Khawplod1, Tanpetch Tantawichien, Henry Wilde, Sukunya Limusanno, Terapong Tantawichien, Apinya Saikasem, Somsri Raksakate.   

Abstract

Storing freshly reconstituted purified chick embryo rabies vaccine at 4 degrees C for 1 week allowed use of <1 ampoule of 1.0 mL for 1 patient for day 0, 3, and 7 immunizations, representing considerable savings in vaccine and also possibly allowing use of this cost-saving regimen in centers that see <1 rabies-exposed patient daily. The 90-day booster dose mandated in the current intradermal regimen may not be necessary if the day 28 dose is doubled, eliminating 1 clinic visit at no additional cost in vaccine.

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Year:  2001        PMID: 11774089     DOI: 10.1086/324507

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  2 in total

1.  Evaluation of a new five-injection, two-site,intradermal schedule for purified chick embryo cell rabies vaccine: A randomized, open-label, active-controlled trial in healthy adult volunteers in India.

Authors:  M K Sudarshan; S N Madhusudana; B J Mahendra; D H Ashwath Narayana; M S Ananda Giri; O Popova; H B Vakil
Journal:  Curr Ther Res Clin Exp       Date:  2005-07

2.  A simplified 4-site economical intradermal post-exposure rabies vaccine regimen: a randomised controlled comparison with standard methods.

Authors:  Mary J Warrell; Anna Riddell; Ly-Mee Yu; Judith Phipps; Linda Diggle; Hervé Bourhy; Jonathan J Deeks; Anthony R Fooks; Laurent Audry; Sharon M Brookes; François-Xavier Meslin; Richard Moxon; Andrew J Pollard; David A Warrell
Journal:  PLoS Negl Trop Dis       Date:  2008-04-23
  2 in total

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