Literature DB >> 11772706

Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: effects on transitional naive T cells (CD4(+)CD45RA(+)CD29(+)).

Michael H Antoni1, Dean G Cruess, Nancy Klimas, Kevin Maher, Stacy Cruess, Mahendra Kumar, Susan Lutgendorf, Gail Ironson, Neil Schneiderman, Mary Ann Fletcher.   

Abstract

OBJECTIVE: Changes in immunologic status were evaluated in 25 HIV-infected men randomly assigned to a 10-week stress management intervention or a wait-list control condition.
METHOD: The authors monitored changes in number of transitional naive T cells (CD4(+)CD45RA(+)CD29(+)) over 6-12 months after the completion of the intervention.
RESULTS: Men receiving stress management had higher CD4(+) CD45RA(+)CD29(+) cell counts at follow-up than did the control subjects. This difference was independent of initial number of naive T cells and HIV virus load.
CONCLUSIONS: Stress management is associated with immunologic reconstitution in HIV-positive gay men.

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Year:  2002        PMID: 11772706     DOI: 10.1176/appi.ajp.159.1.143

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


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