Literature DB >> 11771399

Fluorescence approaches to study G protein mechanisms.

Dyke P McEwen1, Kyle R Gee, Hee C Kang, Richard R Neubig.   

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Year:  2002        PMID： 11771399     DOI： 10.1016/s0076-6879(02)44730-1

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


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  12 in total

1.  Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled gamma-phosphate-linked GTP analogs.

Authors:  Jonas Korlach; Daniel W Baird; Ahmed A Heikal; Kyle R Gee; Gregory R Hoffman; Watt W Webb
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-18       Impact factor: 11.205

2.  Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.

Authors:  Thung-S Lai; Yusha Liu; Tim Tucker; Kurt R Daniel; David C Sane; Eric Toone; James R Burke; Warren J Strittmatter; Charles S Greenberg
Journal:  Chem Biol       Date:  2008-09-22

3.  Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.

Authors:  Chris R Evelyn; Xin Duan; Jacek Biesiada; William L Seibel; Jaroslaw Meller; Yi Zheng
Journal:  Chem Biol       Date:  2014-11-20

4.  Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme.

Authors:  Chris R Evelyn; Jacek Biesiada; Xin Duan; Hong Tang; Xun Shang; Ruben Papoian; William L Seibel; Sandra Nelson; Jaroslaw Meller; Yi Zheng
Journal:  J Biol Chem       Date:  2015-03-30       Impact factor: 5.157

5.  Gαi2 signaling: friend or foe in cardiac injury and heart failure?

Authors:  Kuljeet Kaur; Sergio Parra; Rong Chen; Raelene A Charbeneau; Susan M Wade; Patrick Y Jay; Richard R Neubig
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2012-03-14       Impact factor: 3.000

6.  Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution.

Authors:  Anita M Preininger; Ali I Kaya; James A Gilbert; Laura S Busenlehner; Richard N Armstrong; Heidi E Hamm
Journal:  Biochemistry       Date:  2012-02-22       Impact factor: 3.162

7.  A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization.

Authors:  Robin E Muller; Klara R Klein; Stephanie Q Hutsell; David P Siderovski; Adam J Kimple
Journal:  Assay Drug Dev Technol       Date:  2010-07-27       Impact factor: 1.738

8.  Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain.

Authors:  Jingling Liao; Chun-Xiang Wu; Christopher Burlak; Sheng Zhang; Heather Sahm; Mu Wang; Zhong-Yin Zhang; Kurt W Vogel; Mark Federici; Steve M Riddle; R Jeremy Nichols; Dali Liu; Mark R Cookson; Todd A Stone; Quyen Q Hoang
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-03       Impact factor: 11.205

9.  High-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assay.

Authors:  Chris R Evelyn; Timothy Ferng; Rafael J Rojas; Martha J Larsen; John Sondek; Richard R Neubig
Journal:  J Biomol Screen       Date:  2009-02-04

10.  Identification of two GTP-independent alternatively spliced forms of tissue transglutaminase in human leukocytes, vascular smooth muscle, and endothelial cells.

Authors:  Thung-S Lai; Yusha Liu; Weidong Li; Charles S Greenberg
Journal:  FASEB J       Date:  2007-07-03       Impact factor: 5.191
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