Literature DB >> 11768698

Surgery for pediatric subglottic stenosis: disease-specific outcomes.

C J Hartnick1, B E Hartley, P D Lacy, J Liu, J P Willging, C M Myer, R T Cotton.   

Abstract

To set the foundation to develop a disease-based, operation-specific model to predict the outcome of pediatric airway reconstruction surgery, we performed a retrospective database review of children operated on at a single, tertiary-care children's hospital. Over the 12-year period 1988 to 2000, a total of 1,296 airway reconstruction procedures were performed. Out of these, charts were identified for 199 children who underwent laryngotracheal reconstruction for a sole diagnosis of subglottic stenosis. Children were excluded from the study if their disorder included supraglottic, glottic, or upper tracheal disease. The main outcome measures were Myer-Cotton grade-specific decannulation and extubation rates, including both operation-specific and overall results. There were 101 children who underwent double-stage laryngotracheal reconstruction. The operation-specific decannulation rates for Myer-Cotton grades 2, 3, and 4 were 85% (18/21), 37% (23/61), and 50% (7/14) (chi2 analysis, p = .0007). The overall decannulation rates were 95% (20/21), 74% (45/61), and 86% (12/14) (chi2 analysis, p = .04). There were 98 children who underwent single-stage laryngotracheal reconstruction. The operation-specific extubation rates for Myer-Cotton grades 2, 3, and 4 were 82% (37/45), 79% (34/43), and 67% (2/3) (chi2 analysis, p = .63). The overall extubation rates were 100% (45/45), 86% (37/43), and 100% (3/3) (chi2 analysis, p = .03). Logistic regression analysis showed no effect of age (less than or greater than 2 years of age) on operation-specific or overall outcome parameters. We conclude that laryngotracheal reconstruction for pediatric subglottic stenosis remains a challenging set of procedures in which multiple operations may be required to achieve eventual extubation or decannulation. Children with Myer-Cotton grade 3 or 4 disease continue to represent a significant challenge, and refinements of techniques are being examined to address this subset of children. Disease-based, operation-specific outcome statistics are the first step in the development of a meaningful predictive model.

Entities:  

Mesh:

Year:  2001        PMID: 11768698     DOI: 10.1177/000348940111001204

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  11 in total

1.  Pediatric laryngotracheal reconstruction with tissue-engineered cartilage in a rabbit model.

Authors:  Ian N Jacobs; Robert A Redden; Rachel Goldberg; Michael Hast; Rebecca Salowe; Robert L Mauck; Edward J Doolin
Journal:  Laryngoscope       Date:  2015-10-15       Impact factor: 3.325

2.  Experimental validation of laryngotracheal growth and recurrent laryngeal nerve preservation after partial cricotracheal resection in a growing rabbit model.

Authors:  Keiichi Morita; Kosaku Maeda; Insu Kawahara; Yuko Bitoh
Journal:  Pediatr Surg Int       Date:  2018-07-28       Impact factor: 1.827

3.  Causes and consequences of adult laryngotracheal stenosis.

Authors:  Alexander Gelbard; David O Francis; Vlad C Sandulache; John C Simmons; Donald T Donovan; Julina Ongkasuwan
Journal:  Laryngoscope       Date:  2014-10-07       Impact factor: 3.325

Review 4.  Pediatric airway surgery.

Authors:  Konrad Hoetzenecker; Thomas Schweiger; Doris Maria Denk-Linnert; Walter Klepetko
Journal:  J Thorac Dis       Date:  2017-06       Impact factor: 2.895

5.  Treatment of Childhood High-Grade Subglottic Stenosis (SGS) Through Laryngotracheoplasty (LTP) in a Tertiary Pediatric Center from 2013 to 2020.

Authors:  Talal Al-Khatib; Anas Kurdi; Wafa Abdullah Maqbul; Abdulrahman Maqboul; Talal Alghamdi
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2021-08-03

6.  Scaffold-free tissue-engineered cartilage implants for laryngotracheal reconstruction.

Authors:  David A Gilpin; Mark S Weidenbecher; James E Dennis
Journal:  Laryngoscope       Date:  2010-03       Impact factor: 3.325

7.  Quantitative assessment of the upper airway in infants and children with subglottic stenosis.

Authors:  Carlton Zdanski; Stephanie Davis; Yi Hong; Di Miao; Cory Quammen; Sorin Mitran; Brad Davis; Marc Niethammer; Julia Kimbell; Elizabeth Pitkin; Jason Fine; Lynn Fordham; Bradley Vaughn; Richard Superfine
Journal:  Laryngoscope       Date:  2015-07-30       Impact factor: 3.325

Review 8.  Pathologies of the larynx and trachea in childhood.

Authors:  Christian Sittel
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2014-12-01

9.  Gene therapy of c-myc suppressor FUSE-binding protein-interacting repressor by Sendai virus delivery prevents tracheal stenosis.

Authors:  Daisuke Mizokami; Koji Araki; Nobuaki Tanaka; Hiroshi Suzuki; Masayuki Tomifuji; Taku Yamashita; Yasuji Ueda; Hideaki Shimada; Kazuyuki Matsushita; Akihiro Shiotani
Journal:  PLoS One       Date:  2015-01-08       Impact factor: 3.240

10.  Pediatric airway reconstruction: results after implementation of an airway team in Brazil.

Authors:  Rebecca Maunsell; Nayara Soares Lacerda; Luciahelena Prata; Marcelo Brandão
Journal:  Braz J Otorhinolaryngol       Date:  2018-12-11
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.