Literature DB >> 11765392

Impact of chemical warfare with agent orange on women's reproductive lives in Vietnam: a pilot study.

T N Le1, A Johansson.   

Abstract

During the American war in Vietnam, huge quantities of the highly toxic herbicide dioxin ('Agent Orange'), were sprayed over large areas of central and south Vietnam. In addition to polluting the environment and causing cancers and other diseases in those directly exposed to it, dioxin has caused high rates of pregnancy loss, congenital birth defects and other health problems in their children. This paper reports the findings of a pilot study in the year 2000 among 30 Vietnamese women whose husbands and/or who themselves were exposed to Agent Orange. The aim was to develop research in order to explore the impact of chemical warfare on people's lives. Using the reproductive lifeline and semi-structured interviews, information was gathered on both partners' periods of exposure to Agent Orange, pregnancy outcomes, perceived health problems of children and experiences of living with handicapped children. The women had had a high number of miscarriages and premature births. About two-thirds of their children had congenital malformations or developed disabilities within the first years of life. Most of the families were poor, aggravated by impaired health in the men, the burden of caring for disabled children, and feelings of guilt and inferiority. The plight of 'Agent Orange families' is special and should be placed in its historical and political context.

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Year:  2001        PMID: 11765392     DOI: 10.1016/s0968-8080(01)90102-8

Source DB:  PubMed          Journal:  Reprod Health Matters        ISSN: 0968-8080


  10 in total

1.  Developmental dioxin exposure of either parent is associated with an increased risk of preterm birth in adult mice.

Authors:  Tianbing Ding; Melinda McConaha; Kelli L Boyd; Kevin G Osteen; Kaylon L Bruner-Tran
Journal:  Reprod Toxicol       Date:  2010-11-18       Impact factor: 3.143

2.  Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis.

Authors:  Tultul Nayyar; Kaylon L Bruner-Tran; Dagmara Piestrzeniewicz-Ulanska; Kevin G Osteen
Journal:  Reprod Toxicol       Date:  2006-09-30       Impact factor: 3.143

3.  Developmental exposure to TCDD reduces fertility and negatively affects pregnancy outcomes across multiple generations.

Authors:  Kaylon L Bruner-Tran; Kevin G Osteen
Journal:  Reprod Toxicol       Date:  2010-10-16       Impact factor: 3.143

Review 4.  Environmental Exposure to Endocrine Disrupting Chemicals Influences Genomic Imprinting, Growth, and Metabolism.

Authors:  Nicole Robles-Matos; Tre Artis; Rebecca A Simmons; Marisa S Bartolomei
Journal:  Genes (Basel)       Date:  2021-07-28       Impact factor: 4.096

Review 5.  Environmental contaminant exposures and preterm birth: a comprehensive review.

Authors:  Kelly K Ferguson; Marie S O'Neill; John D Meeker
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2013       Impact factor: 6.393

6.  Congenital malformations in Japanese macaques (Macaca fuscata) at Takasakiyama.

Authors:  Yukimaru Sugiyama; Hiroyuki Kurita; Takeshi Matsui; Satoshi Kimoto; Junko Egawa
Journal:  Primates       Date:  2014-01-29       Impact factor: 2.163

Review 7.  Endocrine disruption of the epigenome: a breast cancer link.

Authors:  Kevin C Knower; Sarah Q To; Yuet-Kin Leung; Shuk-Mei Ho; Colin D Clyne
Journal:  Endocr Relat Cancer       Date:  2014-03-12       Impact factor: 5.678

Review 8.  Dioxin and endometrial progesterone resistance.

Authors:  Kaylon L Bruner-Tran; Tianbing Ding; Kevin G Osteen
Journal:  Semin Reprod Med       Date:  2010-01-26       Impact factor: 1.303

9.  Maternal serum dioxin levels and birth outcomes in women of Seveso, Italy.

Authors:  Brenda Eskenazi; Paolo Mocarelli; Marcella Warner; Wan-Ying Chee; Pier Mario Gerthoux; Steven Samuels; Larry L Needham; Donald G Patterson
Journal:  Environ Health Perspect       Date:  2003-06       Impact factor: 9.031

10.  Relationship of serum TCDD concentrations and age at exposure of female residents of Seveso, Italy.

Authors:  Brenda Eskenazi; Paolo Mocarelli; Marcella Warner; Larry Needham; Donald G Patterson; Steven Samuels; Wayman Turner; Pier Mario Gerthoux; Paolo Brambilla
Journal:  Environ Health Perspect       Date:  2004-01       Impact factor: 9.031

  10 in total

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