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Literature DB >> 11765050

An exception to the rule: ectopic ACTH production from functional neuroendocrine tissue in an ovarian dermoid cyst.

J Watson¹, M Taylor, J Pampiglione, S Rasbridge, M Armitage.

Abstract

Ectopic ACTH production accounts for 15% of Cushing's syndrome presentations and is characterized by the presence of an excess of ACTH precursors. However in the case presented here ectopic ACTH production was from functional pituitary tissue within an ovarian dermoid cyst. Endocrine investigations showed that the problem behaved more like pituitary-dependent Cushing's disease and this is discussed. Furthermore, this case is one of familial dermoid cysts, another unusual phenomenon.

Entities: Disease Gene

Mesh：

Substances：

Year: 2001 PMID： 11765050 DOI： 10.1007/BF03343930

Source DB: PubMed Journal: J Endocrinol Invest ISSN： 0391-4097 Impact factor: 4.256

15 in total

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Authors: D Linder; B K McCaw; F Hecht
Journal: N Engl J Med Date: 1975-01-09 Impact factor: 91.245

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Journal: Postgrad Med J Date: 1996-03 Impact factor: 2.401

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Journal: Clin Endocrinol (Oxf) Date: 1987-01 Impact factor: 3.478

6. An evaluation of the distinction of ectopic and pituitary ACTH dependent Cushing's syndrome by clinical features, biochemical tests and radiological findings.

Authors: S B Blunt; L M Sandler; J M Burrin; G F Joplin
Journal: Q J Med Date: 1990-11

Review 2. Dual-tracer PET/CT imaging to determine tumor heterogeneity in a patient with metastatic ACTH-secreting neuroendocrine neoplasm: A case report and literature review.

Authors: Daria Ryzhkova; Lubov Mitrofanova; Uliana Tsoy; Elena Grineva; Evgeny Schlyakhto
Journal: Front Endocrinol (Lausanne) Date: 2022-09-05 Impact factor: 6.055

2 in total

An exception to the rule: ectopic ACTH production from functional neuroendocrine tissue in an ovarian dermoid cyst.

1. Parthenogenic origin of benign ovarian teratomas.

2. Ectopic ACTH syndrome: redefinition and case report.

Review 3. Familial ovarian dermoids.

4. Pituitary-containing benign cystic teratoma of the ovary in a patient with metastatic breast cancer: a case report.

5. Clinical evaluation of a two-site immunoradiometric assay for adrenocorticotrophin in unextracted human plasma using monoclonal antibodies.

6. An evaluation of the distinction of ectopic and pituitary ACTH dependent Cushing's syndrome by clinical features, biochemical tests and radiological findings.

7. Anterior pituitary component in benign cystic ovarian teratomas. Report of three cases.

8. Prolactinoma in wall of ovarian dermoid cyst with hyperprolactinemia.

9. Impaired processing of proopiomelanocortin in corticotroph macroadenomas.

10. ACTH precursors characterize the ectopic ACTH syndrome.

1. Endocrine pathology of the ovary : in tribute to Robert E Scully, MD.

Review 2. Dual-tracer PET/CT imaging to determine tumor heterogeneity in a patient with metastatic ACTH-secreting neuroendocrine neoplasm: A case report and literature review.