Literature DB >> 11765013

Identification of hepatic protein targets of the reactive metabolites of the non-hepatotoxic regioisomer of acetaminophen, 3'-hydroxyacetanilide, in the mouse in vivo using two-dimensional gel electrophoresis and mass spectrometry.

Y Qiu1, L Z Benet, A L Burlingame.   

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Year:  2001        PMID: 11765013     DOI: 10.1007/978-1-4615-0667-6_99

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


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  26 in total

1.  c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.

Authors:  Chieko Saito; John J Lemasters; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2010-04-25       Impact factor: 4.219

2.  HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity.

Authors:  Mitchell R McGill; Hui-Min Yan; Anup Ramachandran; Gordon J Murray; Douglas E Rollins; Hartmut Jaeschke
Journal:  Hepatology       Date:  2011-02-11       Impact factor: 17.425

3.  Renal function and arterial blood pressure alterations after exposure to acetaminophen with a potential role of Nigella sativa oil in adult male rats.

Authors:  Omyma Galal Ahmed; Nashwa Aly Abd El-Mottaleb
Journal:  J Physiol Biochem       Date:  2012-06-23       Impact factor: 4.158

4.  Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.

Authors:  Yuchao Xie; Mitchell R McGill; Kuo Du; Kenneth Dorko; Sean C Kumer; Timothy M Schmitt; Wen-Xing Ding; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2015-09-30       Impact factor: 4.219

5.  Acetaminophen Hepatotoxicity.

Authors:  Anup Ramachandran; Hartmut Jaeschke
Journal:  Semin Liver Dis       Date:  2019-03-08       Impact factor: 6.115

Review 6.  Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity.

Authors:  Hartmut Jaeschke; C David Williams; Anup Ramachandran; Mary L Bajt
Journal:  Liver Int       Date:  2011-03-14       Impact factor: 5.828

7.  The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Authors:  Hui-Min Yan; Anup Ramachandran; Mary Lynn Bajt; John J Lemasters; Hartmut Jaeschke
Journal:  Toxicol Sci       Date:  2010-07-08       Impact factor: 4.849

8.  Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity.

Authors:  Benjamin L Woolbright; Anup Ramachandran; Mitchell R McGill; Hui-min Yan; Mary Lynn Bajt; Matthew R Sharpe; John J Lemasters; Hartmut Jaeschke
Journal:  Basic Clin Pharmacol Toxicol       Date:  2012-09-25       Impact factor: 4.080

9.  Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

Authors:  Chieko Saito; Hui-Min Yan; Antonio Artigues; Maria T Villar; Anwar Farhood; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2009-10-14       Impact factor: 4.219

Review 10.  Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products.

Authors:  Hartmut Jaeschke; C David Williams; Mitchell R McGill; Yuchao Xie; Anup Ramachandran
Journal:  Food Chem Toxicol       Date:  2013-01-22       Impact factor: 6.023

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