Literature DB >> 11764926

Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation.

M Belghazi1, P Jean, S Poli, J M Schmitter, D Mansuy, P M Dansette.   

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Year:  2001        PMID： 11764926     DOI： 10.1007/978-1-4615-0667-6_17

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


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  4 in total

1.  Development of an in vitro system with human liver microsomes for phenotyping of CYP2C9 genetic polymorphisms with a mechanism-based inactivator.

Authors:  Darcy R Flora; Timothy S Tracy
Journal:  Drug Metab Dispos       Date:  2011-12-28       Impact factor: 3.922

2.  Identification of protein targets of reactive metabolites of tienilic acid in human hepatocytes.

Authors:  Yakov M Koen; Diganta Sarma; Todd D Williams; Nadezhda A Galeva; R Scott Obach; Robert P Hanzlik
Journal:  Chem Res Toxicol       Date:  2012-04-10       Impact factor: 3.739

3.  Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9.

Authors:  Peter M Rademacher; Caleb M Woods; Qingbiao Huang; Grazyna D Szklarz; Sidney D Nelson
Journal:  Chem Res Toxicol       Date:  2012-03-14       Impact factor: 3.739

Review 4.  Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation.

Authors:  Derek R Boyd; Narain D Sharma; Paul J Stevenson; Patrick Hoering; Christopher C R Allen; Patrick M Dansette
Journal:  Int J Mol Sci       Date:  2022-01-14       Impact factor: 5.923
  4 in total

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