Literature DB >> 1176186

Mast cell and anaphylactic antibody responses in inbred rats to syngeneic fibrosarcomas.

B C Broom, P Alexander.   

Abstract

The mast cell content of sarcomata induced chemically in inbred rats showed wide variation. After first passage into a normal syngeneic recipient, primary tumours which were heavily infiltrated showed a complete absence of mast cells. Moreover, detectable anaphylactic antibody to passaged tumours was only occasionally detected. An important immunological role for the IgE/mast cell system in host-tumour defence is not supported.

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Year:  1975        PMID: 1176186     DOI: 10.1159/000231444

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN: 0020-5915


  2 in total

1.  Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor.

Authors:  J D Young; C C Liu; G Butler; Z A Cohn; S J Galli
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

2.  Mast cell modulation of tumour cell proliferation in rat mammary adenocarcinoma 13762NF.

Authors:  M K Dabbous; L Haney; G L Nicolson; D Eckley; D E Woolley
Journal:  Br J Cancer       Date:  1991-06       Impact factor: 7.640

  2 in total

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