| Literature DB >> 1176186 |
Abstract
The mast cell content of sarcomata induced chemically in inbred rats showed wide variation. After first passage into a normal syngeneic recipient, primary tumours which were heavily infiltrated showed a complete absence of mast cells. Moreover, detectable anaphylactic antibody to passaged tumours was only occasionally detected. An important immunological role for the IgE/mast cell system in host-tumour defence is not supported.Entities:
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Year: 1975 PMID: 1176186 DOI: 10.1159/000231444
Source DB: PubMed Journal: Int Arch Allergy Appl Immunol ISSN: 0020-5915