Literature DB >> 11761506

The management of melanoma and nonmelanoma skin cancer: a review for the primary care physician.

J C Martinez1, C C Otley.   

Abstract

In the United States, the incidence of skin cancer is greater than that of all other cancers combined, and early diagnosis can be lifesaving. A substantial public health concern, skin cancer is increasingly being diagnosed and managed by primary care physicians. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) (known collectively as nonmelanoma skin cancer) and malignant melanoma are the most common cutaneous malignancies. Shave biopsy is usually performed if BCC is suspected; punch biopsy is preferred if SCC is thought to be present. The choice of biopsy techniques depends on the presumed depth of the lesion. Treatment has 3 goals: complete eradication of the cancer and preservation or restoration of normal function and cosmesis. Risk of recurrence or metastasis determines whether the tumor is high risk or low risk. Based on the level of risk, treatment options are considered, including whether the patient can be treated by a primary care physician or should be referred to a dermatologist. Choice of treatment approach depends on the tumor's location, size, borders, and growth rate. The standard treatment approaches are superficial ablative techniques (electro-desiccation and curettage and cryotherapy) used primarily for low-risk tumors and full-thickness techniques (Mohs micrographic surgery, excisional surgery, and radiotherapy) used to treat high-risk tumors. Removal of the entire tumor is essential to limit and prevent tumor recurrence.

Entities:  

Mesh:

Year:  2001        PMID: 11761506     DOI: 10.4065/76.12.1253

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  18 in total

1.  Tazarotene induces apoptosis in human basal cell carcinoma via activation of caspase-8/t-Bid and the reactive oxygen species-dependent mitochondrial pathway.

Authors:  Chieh-Shan Wu; Gwo-Shing Chen; Ping-Yi Lin; I-Hong Pan; San-Tang Wang; Sheng Hao Lin; Hsin-Su Yu; Chi-Chen Lin
Journal:  DNA Cell Biol       Date:  2014-06-13       Impact factor: 3.311

2.  The facial skin lesions "see and treat" clinic: A prospective study.

Authors:  Mahmoud A Salam; Vandana Matai; Mohamed Salhab; A W Hilger
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-05-13       Impact factor: 2.503

Review 3.  Ultrasound-targeted nucleic acid delivery for solid tumor therapy.

Authors:  Mark R Schwartz; Anna C Debski; Richard J Price
Journal:  J Control Release       Date:  2021-10-14       Impact factor: 11.467

4.  Patient satisfaction with GP-led melanoma follow-up: a randomised controlled trial.

Authors:  P Murchie; M C Nicolson; P C Hannaford; E A Raja; A J Lee; N C Campbell
Journal:  Br J Cancer       Date:  2010-05-11       Impact factor: 7.640

Review 5.  Nonmelanoma skin cancer.

Authors:  Tri H Nguyen; Diana Quynh-Dao Ho
Journal:  Curr Treat Options Oncol       Date:  2002-06

Review 6.  Basal Cell Carcinoma Surgery in general practice: Is there a role for the local General Practitioner?

Authors:  S H Keah; S C Ng
Journal:  Malays Fam Physician       Date:  2020-11-10

7.  Neck dissection and post-operative chemotherapy with dimethyl triazeno imidazole carboxamide and cisplatin protocol are useful for oral mucosal melanoma.

Authors:  Xi Yang; Guo-Xin Ren; Chen-Ping Zhang; Guo-Yu Zhou; Yong-Jie Hu; Wen-Jun Yang; Wei Guo; Jiang Li; Lai-Ping Zhong
Journal:  BMC Cancer       Date:  2010-11-11       Impact factor: 4.430

Review 8.  A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis.

Authors:  Andrew Croaker; Graham J King; John H Pyne; Shailendra Anoopkumar-Dukie; Lei Liu
Journal:  Evid Based Complement Alternat Med       Date:  2017-01-26       Impact factor: 2.629

9.  Longitudinal, mixed method study to look at the experiences and knowledge of non melanoma skin cancer from diagnosis to one year.

Authors:  Fiona Bath-Hextall; Claire Jenkinson; Arun Kumar; Jo Leonardi-Bee; William Perkins; Karen Cox; Cris Glazebrook
Journal:  BMC Dermatol       Date:  2013-10-29

Review 10.  Chronic Inflammation in Skin Malignancies.

Authors:  Lihua Tang; Kepeng Wang
Journal:  J Mol Signal       Date:  2016-05-05
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