Study of a yeast mutant with modified mitochondrial translocation of adenine nucleotides. II. Synthesis of macromolecules and lipids in the op1 mutant during mutagenesis with ethidium bromide.

A yeast mutant with an impaired system of translocation of adenine nucleotides across the mitochondrial membrane, which stops dividing after superposition of the q- mutation, was investigated. The results of this work indicate that combination of the op1 mutation with the q- mutation in a single cell results in interruption of synthesis of polysaccharides and DNA leading to cessation of division of the op1q- mutant. The mechanism of this effect remains unclear.