Literature DB >> 11758457

DNA methylation and control of gene expression in vertebrate development.

R R Meehan1, I Stancheva.   

Abstract

MeCpGs act as ligands for nuclear factors (repressors) that are components of chromatin modification and remodelling activities. The DNA-methylation-mediated repression system (Dnmt1s, MeCPs and MBDs) is highly conserved in vertebrates. DNA methylation is essential for normal vertebrate development. It is possible (but remains unproven) that the role of DNA methylation in regulating development is highly conserved in vertebrates. In mammals, DNA methylation has an additional role in regulating the expression of imprinted genes and in controlling X-inactivation.

Mesh：

Year:  2001        PMID： 11758457     DOI： 10.1042/bse0370059

Source DB:  PubMed          Journal:  Essays Biochem        ISSN： 0071-1365            Impact factor:   8.000


  12 in total

Review 1.  Nuclear reprogramming and stem cell creation.

Authors:  J B Gurdon; J A Byrne; S Simonsson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-14       Impact factor: 11.205

2.  MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos.

Authors:  Alexey Ruzov; Boris Shorning; Oliver Mortusewicz; Donncha S Dunican; Heinrich Leonhardt; Richard R Meehan
Journal:  Development       Date:  2009-07       Impact factor: 6.868

3.  Neuronal pentraxin II (NPTX2) is frequently down-regulated by promoter hypermethylation in pancreatic cancers.

Authors:  Ling Zhang; Jun Gao; Zhaoshen Li; Yanfang Gong
Journal:  Dig Dis Sci       Date:  2012-07-18       Impact factor: 3.199

4.  Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins.

Authors:  Matthew J Lyst; Xinsheng Nan; Irina Stancheva
Journal:  EMBO J       Date:  2006-10-26       Impact factor: 11.598

5.  The Molecular Differentiation of Anatomically Paired Left and Right Mantles of the Pacific Oyster Crassostrea gigas.

Authors:  Lei Wei; Fei Xu; Yuzhi Wang; Zhongqiang Cai; Wenchao Yu; Cheng He; Qiuyun Jiang; Xiqiang Xu; Wen Guo; Xiaotong Wang
Journal:  Mar Biotechnol (NY)       Date:  2018-03-28       Impact factor: 3.619

6.  Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.

Authors:  Ahmed H Badran; Jennifer L Furman; Andrew S Ma; Troy J Comi; Jason R Porter; Indraneel Ghosh
Journal:  Anal Chem       Date:  2011-08-23       Impact factor: 6.986

7.  Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors.

Authors:  Allison B Weisbrod; Lisa Zhang; Meenu Jain; Stephanie Barak; Martha M Quezado; Electron Kebebew
Journal:  Horm Cancer       Date:  2013-01-30       Impact factor: 3.869

8.  Chromatin structure and DNA methylation of the IL-4 gene in human T(H)2 cells.

Authors:  Samantha Santangelo; David J Cousins; Nicole Winkelmann; Kostas Triantaphyllopoulos; Dontcho Z Staynov
Journal:  Chromosome Res       Date:  2009-06-12       Impact factor: 5.239

9.  Novel methyltransferase for modified uridine residues at the wobble position of tRNA.

Authors:  Hamid R Kalhor; Steven Clarke
Journal:  Mol Cell Biol       Date:  2003-12       Impact factor: 4.272

Review 10.  Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?

Authors:  T Clouaire; I Stancheva
Journal:  Cell Mol Life Sci       Date:  2008-05       Impact factor: 9.261
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