Literature DB >> 1175733

Chlorodimeform and its effect on monoamine oxidase activity in the cattle tick, Boophilus microplus.

J S Holden, J R Hadfield.   

Abstract

The action of the acaricide, chlorodimeform and its metabolite. N-desmethylchlorodimeform, on the activity monoamine oxidase (MAO) from the cattle tick, Boophilus microplus, were studied. Both compounds were found to be potent in vitro and in vivo inhibitors of the enzyme. However the inhibition of MAO does not seem to be related to the toxic action of the acaricide.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1175733     DOI： 10.1007/bf02326931

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE.

Authors:  R J WURTMAN; J AXELROD
Journal:  Biochem Pharmacol       Date:  1963-12       Impact factor: 5.858

2.  Chlordimeform: the relation of mitochondrial uncoupling to toxicity in the German cockroach.

Authors:  N Abo-Khatwa; R M Hollingworth
Journal:  Life Sci II       Date:  1972-12-22

3.  Chlordimeform: a pesticide acting upon amine regulatory mechanisms.

Authors:  R W Beeman; F Matsumura
Journal:  Nature       Date:  1973-03-23       Impact factor: 49.962

4.  Inhibition of monoamine oxidase by the pesticide chlordimeform and related compounds.

Authors:  S A Aziz; C O Knowles
Journal:  Nature       Date:  1973-04-06       Impact factor: 49.962

5.  Toxicity to Boophilus microplus of formamidine acaricides and related compounds, and modification of toxicity by certain insecticide synergists.

Authors:  C O Knowles; W J Roulston
Journal:  J Econ Entomol       Date:  1973-12       Impact factor: 2.381

6.  Metabolism of N'-(4-chloro-o-tolyl)-N,N-dimethylformamidine (chlorphenamidine) and 4'-chloro-o-formotoluidide by rat hepatic microsomal and soluble enzymes.

Authors:  S Ahmad; C O Knowles
Journal:  Comp Gen Pharmacol       Date:  1971-06
  6 in total
  1 in total

1.  MAO inhibition, an unlikely mode of action for chlordimeform.

Authors:  R Neumann; G Voss
Journal:  Experientia       Date:  1977-01-15
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.