| Literature DB >> 11754615 |
R J Clark1, M J Garson, J N Hooper.
Abstract
Three new amino alcohols presumably deriving from L-alanine were isolated from the tropical marine sponge Haliclona n. sp. and characterized by 2D NMR, while a fourth amino alcohol was characterized as an acetamide derivative. Relative stereochemistry was deduced from the NMR characteristics of oxazolidinone derivatives and absolute stereochemistry secured by preparation and analysis of an MPA ester. The amino alcohol fraction from Haliclona n. sp. acts as an antifungal agent and inhibits the development of larvae of the ascidian Herdmania curvata.Entities:
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Year: 2001 PMID： 11754615 DOI： 10.1021/np010246x
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050