Literature DB >> 11754614

Cytotoxic polyacetylenic alcohols from the marine sponge Petrosia species.

Y J Lim1, C O Lee, J Hong, D K Kim, K S Im, J H Jung.   

Abstract

New polyacetylenic alcohols (1-5) have been isolated as cytotoxic principles from the marine sponge Petrosia sp. The compounds were particularly cytotoxic against a human melanoma cell line (SK-MEL-2). The gross structures were established on the basis of NMR and MS data, and the absolute configuration was determined by the modified Mosher's method.

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Year:  2001        PMID: 11754614     DOI: 10.1021/np010247p

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  7 in total

1.  Assignment of the structure of petrocortyne A by mixture syntheses of four candidate stereoisomers.

Authors:  Bin Sui; Edmund A-H Yeh; Dennis P Curran
Journal:  J Org Chem       Date:  2010-05-07       Impact factor: 4.354

Review 2.  Biosynthesis and function of polyacetylenes and allied natural products.

Authors:  Robert E Minto; Brenda J Blacklock
Journal:  Prog Lipid Res       Date:  2008-03-13       Impact factor: 16.195

3.  A "shortcut" Mosher ester method to assign configurations of stereocenters in nearly symmetric environments. Fluorous mixture synthesis and structure assignment of petrocortyne A.

Authors:  Dennis P Curran; Bin Sui
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

4.  In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges.

Authors:  Sungyoul Hong; Sung Hwan Kim; Man Hee Rhee; Ae Ra Kim; Jee H Jung; Taehoon Chun; Eun Sook Yoo; Jae Youl Cho
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-11-13       Impact factor: 3.000

5.  Actinobacteria associated with the marine sponges Cinachyra sp., Petrosia sp., and Ulosa sp. and their culturability.

Authors:  Shams Tabrez Khan; Motoki Takagi; Kazuo Shin-ya
Journal:  Microbes Environ       Date:  2011-12-29       Impact factor: 2.912

6.  Structure elucidation and cytotoxic evaluation of new polyacetylenes from a marine sponge Petrosia sp.

Authors:  Yung-Shun Juan; Chien-Chih Lee; Chia-Wei Tsao; Mei-Chin Lu; Mohamed El-Shazly; Huei-Chuan Shih; Yu-Cheng Chen; Yang-Chang Wu; Jui-Hsin Su
Journal:  Int J Mol Sci       Date:  2014-09-18       Impact factor: 5.923

Review 7.  Secondary Metabolites from the Marine Sponges of the Genus Petrosia: A Literature Review of 43 Years of Research.

Authors:  Yeon-Ju Lee; Yeonwoo Cho; Huynh Nguyen Khanh Tran
Journal:  Mar Drugs       Date:  2021-02-25       Impact factor: 5.118

  7 in total

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