Literature DB >> 11752636

Membrane cholesterol, protein phosphorylation, and lipid rafts.

M Edidin1.   

Abstract

The functions of cholesterol and membrane microdomains in transmembrane signaling remain controversial. Edidin discusses the questions surrounding lipid rafts, membrane microdomains that have been biochemically defined but are difficult to visualize in vivo. He also discusses whether experiments showing correlation of changes in plasma membrane cholesterol with differentiation and the formation of adherens junctions in endothelial cells are consistent with a model in which lipid rafts influence the regulation of these processes.

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Year:  2001        PMID： 11752636     DOI： 10.1126/stke.2001.67.pe1

Source DB:  PubMed          Journal:  Sci STKE        ISSN： 1525-8882


  7 in total

Review 1.  Ion channels, phosphorylation and mammalian sperm capacitation.

Authors:  Pablo E Visconti; Dario Krapf; José Luis de la Vega-Beltrán; Juan José Acevedo; Alberto Darszon
Journal:  Asian J Androl       Date:  2011-05       Impact factor: 3.285

2.  Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts.

Authors:  Liyan Zhuang; Jayoung Kim; Rosalyn M Adam; Keith R Solomon; Michael R Freeman
Journal:  J Clin Invest       Date:  2005-03-17       Impact factor: 14.808

Review 3.  Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies.

Authors:  Raphael Zidovetzki; Irena Levitan
Journal:  Biochim Biophys Acta       Date:  2007-04-06

4.  Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells.

Authors:  Lawrence Rajendran; Madhan Masilamani; Samuel Solomon; Ritva Tikkanen; Claudia A O Stuermer; Helmut Plattner; Harald Illges
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-25       Impact factor: 12.779

5.  Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells.

Authors:  Hari Raghu; Prasanna Kumar Sodadasu; Rama Rao Malla; Christopher S Gondi; Norman Estes; Jasti S Rao
Journal:  BMC Cancer       Date:  2010-11-24       Impact factor: 4.430

6.  Spatial regulation and the rate of signal transduction activation.

Authors:  Nizar N Batada; Larry A Shepp; David O Siegmund; Michael Levitt
Journal:  PLoS Comput Biol       Date:  2006-05-12       Impact factor: 4.475

7.  Sesquiterpene Alcohol Cedrol Chemosensitizes Human Cancer Cells and Suppresses Cell Proliferation by Destabilizing Plasma Membrane Lipid Rafts.

Authors:  Siddhartha Kumar Mishra; Yun Soo Bae; Yong-Moon Lee; Jae-Sung Kim; Seung Hyun Oh; Hwan Mook Kim
Journal:  Front Cell Dev Biol       Date:  2021-01-21
  7 in total

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