Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Meeting report: signaling schemes for TGF-beta.

Literature DB >> 11752631

Meeting report: signaling schemes for TGF-beta.

Abstract

The transforming growth factor-beta (TGF-beta) superfamily of signaling molecules regulates many developmental processes in a range of organisms from worms to humans. Understanding the mechanisms by which they exert their repertoire of effects has required identification of the components of signaling pathways that they control. Roberts and Derynck focus on this aspect of TGF-beta biology in their review of a recent Federation of American Societies for Experimental Biology (FASEB) meeting on TGF-beta signaling and development and summarize current signaling paradigms and future prospects in TGF-beta signaling from the cell surface to the nucleus.

Entities: Gene Species

Mesh：

Substances：

Year: 2001 PMID： 11752631 DOI： 10.1126/stke.2001.113.pe43

Source DB: PubMed Journal: Sci STKE ISSN： 1525-8882

Keyword Cloud
Cited

11 in total

1. E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.

Authors: Tao Yang; Roberto Mendoza-Londono; Huifang Lu; Jianning Tao; Kaiyi Li; Bettina Keller; Ming Ming Jiang; Rina Shah; Yuqing Chen; Terry K Bertin; Feyza Engin; Branka Dabovic; Daniel B Rifkin; John Hicks; Milan Jamrich; Arthur L Beaudet; Brendan Lee
Journal: J Clin Invest Date: 2010-06-07 Impact factor: 14.808

2. Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription.

Authors: Xia Lin; Yao-Yun Liang; Baohua Sun; Min Liang; Yujiang Shi; F Charles Brunicardi; Yang Shi; Xin-Hua Feng
Journal: Mol Cell Biol Date: 2003-12 Impact factor: 4.272

3. TGF-{beta}1 protects against mesangial cell apoptosis via induction of autophagy.

Authors: Yan Ding; Jin Kuk Kim; Sung Il Kim; Hee-Jun Na; Soo Young Jun; Seon Jin Lee; Mary E Choi
Journal: J Biol Chem Date: 2010-09-28 Impact factor: 5.157

4. Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3.

Authors: Alice Banh; Paula A Deschamps; Jack Gauldie; Paul A Overbeek; Jacob G Sivak; Judith A West-Mays
Journal: Invest Ophthalmol Vis Sci Date: 2006-08 Impact factor: 4.799

5. Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

Authors: Jeffrey C Horowitz; Daniel Y Lee; Meghna Waghray; Venkateshwar G Keshamouni; Peedikayil E Thomas; Hengmin Zhang; Zongbin Cui; Victor J Thannickal
Journal: J Biol Chem Date: 2003-10-23 Impact factor: 5.157

6. Retinoids regulate TGFbeta signaling at the level of Smad2 phosphorylation and nuclear accumulation.

Authors: Loretta L Hoover; Elizabeth G Burton; Megan L O'Neill; Bonnie A Brooks; Shilpa Sreedharan; Nineveh A Dawson; Steven W Kubalak
Journal: Biochim Biophys Acta Date: 2008-08-13

7. Role of extracellular signal-regulated kinase, p38 kinase, and activator protein-1 in transforming growth factor-beta1-induced alpha smooth muscle actin expression in human fetal lung fibroblasts in vitro.

Authors: Yongbin Hu; Jinwu Peng; Deyun Feng; Ling Chu; Xiang Li; Zhongyuan Jin; Zhi Lin; Qingfu Zeng
Journal: Lung Date: 2006 Jan-Feb Impact factor: 3.777