Literature DB >> 11751232

MELTING, computing the melting temperature of nucleic acid duplex.

N Le Novère1.   

Abstract

UNLABELLED: MELTING computes the enthalpy and entropy of an oligonucleotide duplex helix-coil transition, and then its melting temperature. The program uses the method of nearest-neighbours. The set of thermodynamic parameters can be easily customized. The program provides several correction methods for the concentration of salt. MELTING is a free program, available at no cost and open-source. Perl scripts are provided to show how MELTING can be used to construct more ambitious programs. AVAILABILITY: MELTING is available for several platforms (http://www.pasteur.fr/recherche/unites/neubiomol/meltinghome.html) and is accessible via a www server (http://bioweb.pasteur.fr/seqanal/interfaces/melting.html). CONTACT: nl223@cus.cam.ac.uk

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Year:  2001        PMID: 11751232     DOI: 10.1093/bioinformatics/17.12.1226

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  49 in total

1.  Probing triplex formation by EPR spectroscopy using a newly synthesized spin label for oligonucleotides.

Authors:  Peter M Gannett; Eva Darian; Jeannine Powell; Edward M Johnson; Claudius Mundoma; Nancy L Greenbaum; Chris M Ramsey; Naresh S Dalal; David E Budil
Journal:  Nucleic Acids Res       Date:  2002-12-01       Impact factor: 16.971

2.  Primer Prim'er: a web based server for automated primer design.

Authors:  John K Everett; Thomas B Acton; Gaetano T Montelione
Journal:  J Struct Funct Genomics       Date:  2004

3.  Development of a new oligonucleotide array to identify staphylococcal strains at species level.

Authors:  Philippe Giammarinaro; Sabine Leroy; Jean-Paul Chacornac; Julien Delmas; Regine Talon
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

4.  Statistical thermodynamics and kinetics of DNA multiplex hybridization reactions.

Authors:  M T Horne; D J Fish; A S Benight
Journal:  Biophys J       Date:  2006-09-08       Impact factor: 4.033

5.  DNA stability in the gas versus solution phases: a systematic study of thirty-one duplexes with varying length, sequence, and charge level.

Authors:  Su Pan; Xuejun Sun; Jeehiun K Lee
Journal:  J Am Soc Mass Spectrom       Date:  2006-08-17       Impact factor: 3.109

6.  Identification of PCR products using PNA amphiphiles in micellar electrokinetic chromatography.

Authors:  Shane T Grosser; Jeffrey M Savard; James W Schneider
Journal:  Anal Chem       Date:  2007-11-20       Impact factor: 6.986

7.  StrBioLib: a Java library for development of custom computational structural biology applications.

Authors:  John-Marc Chandonia
Journal:  Bioinformatics       Date:  2007-05-30       Impact factor: 6.937

8.  Multiplex asymmetric PCR-based oligonucleotide microarray for detection of drug resistance genes containing single mutations in Enterobacteriaceae.

Authors:  Ling-Xiang Zhu; Zhi-Wei Zhang; Dong Liang; Di Jiang; Can Wang; Ning Du; Qiong Zhang; Keith Mitchelson; Jing Cheng
Journal:  Antimicrob Agents Chemother       Date:  2007-07-23       Impact factor: 5.191

9.  A unified Poland-Scheraga model of oligo- and polynucleotide DNA melting: salt effects and predictive power.

Authors:  Daniel Jost; Ralf Everaers
Journal:  Biophys J       Date:  2009-02       Impact factor: 4.033

10.  Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA?

Authors:  Atul Rangadurai; Huiqing Zhou; Dawn K Merriman; Nathalie Meiser; Bei Liu; Honglue Shi; Eric S Szymanski; Hashim M Al-Hashimi
Journal:  Nucleic Acids Res       Date:  2018-11-16       Impact factor: 16.971

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