Literature DB >> 11751141

Gatifloxacin efficacy in treatment of experimental methicillin-sensitive Staphylococcus aureus-induced osteomyelitis in rabbits.

Mark E Shirtliff1, Jason H Calhoun, Jon T Mader.   

Abstract

The effectiveness of oral gatifloxacin was compared to that of standard parenteral antibiotic therapy (nafcillin) for the treatment of experimental methicillin-sensitive Staphylococcus aureus-induced osteomyelitis in a rabbit model. Gatifloxacin was as effective as nafcillin in clearing the infection. Therefore, oral gatifloxacin treatment of osteomyelitis may be an effective alternative to intravenous nafcillin treatment.

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Year:  2002        PMID: 11751141      PMCID: PMC127012          DOI: 10.1128/AAC.46.1.231-233.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  11 in total

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Authors:  F A Waldvogel; G Medoff; M N Swartz
Journal:  N Engl J Med       Date:  1970-01-22       Impact factor: 91.245

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Journal:  Antimicrob Agents Chemother       Date:  1995-12       Impact factor: 5.191

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Authors:  J T Mader; K J Wilson
Journal:  J Bone Joint Surg Am       Date:  1983-04       Impact factor: 5.284

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Journal:  Gastroenterology       Date:  1980-08       Impact factor: 22.682

Review 7.  Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects. 3. Osteomyelitis associated with vascular insufficiency.

Authors:  F A Waldvogel; G Medoff; M N Swartz
Journal:  N Engl J Med       Date:  1970-02-05       Impact factor: 91.245

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Authors:  C M Perry; J A Barman Balfour; H M Lamb
Journal:  Drugs       Date:  1999-10       Impact factor: 9.546

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Authors:  J T Mader
Journal:  Am J Med       Date:  1985-06-28       Impact factor: 4.965

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Authors:  J T Mader; L T Morrison; K R Adams
Journal:  Antimicrob Agents Chemother       Date:  1987-02       Impact factor: 5.191

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  4 in total

1.  [Animal models of osteomyelitis].

Authors:  T Kälicke; U Schlegel; C Kraft; C Wingenfeld; G Muhr; S Arens
Journal:  Orthopade       Date:  2004-03       Impact factor: 1.087

2.  Murine immune response to a chronic Staphylococcus aureus biofilm infection.

Authors:  Ranjani Prabhakara; Janette M Harro; Jeff G Leid; Megan Harris; Mark E Shirtliff
Journal:  Infect Immun       Date:  2011-01-31       Impact factor: 3.441

3.  Development of a Novel and Rapid Antibody-Based Diagnostic for Chronic Staphylococcus aureus Infections Based on Biofilm Antigens.

Authors:  Janette M Harro; Mark E Shirtliff; William Arnold; Jennifer M Kofonow; Chad Dammling; Yvonne Achermann; Kristen Brao; Javad Parvizi; Jeff G Leid
Journal:  J Clin Microbiol       Date:  2020-04-23       Impact factor: 5.948

4.  A different perspective for radiological evaluation of experimental osteomyelitis.

Authors:  Cem Nuri Aktekin; Akif Muhtar Ozturk; Abdullah Yalcin Tabak; Murat Altay; Feza Korkusuz
Journal:  Skeletal Radiol       Date:  2007-07-12       Impact factor: 2.199

  4 in total

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