Literature DB >> 11750700

Getting your Pax straight: Pax proteins in development and disease.

Neil Chi1, Jonathan A Epstein.   

Abstract

The Pax gene family encodes a group of transcription factors that have been conserved through millions of years of evolution and play roles in early development. Pax proteins have been implicated as regulators of organogenesis and as key factors in maintaining pluripotency of stem cell populations during development. Mutations of the Pax genes cause profound developmental defects in organisms as diverse as flies, mice and humans. Here, we review crucial and illustrative roles of Pax gene products in cell-fate specification and developmental biology.

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Year:  2002        PMID： 11750700     DOI： 10.1016/s0168-9525(01)02594-x

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  134 in total

1.  A genomewide survey of developmentally relevant genes in Ciona intestinalis. II. Genes for homeobox transcription factors.

Authors:  Shuichi Wada; Miki Tokuoka; Eiichi Shoguchi; Kenji Kobayashi; Anna Di Gregorio; Antonietta Spagnuolo; Margherita Branno; Yuji Kohara; Daniel Rokhsar; Michael Levine; Hidetoshi Saiga; Nori Satoh; Yutaka Satou
Journal:  Dev Genes Evol       Date:  2003-05-08       Impact factor: 0.900

2.  Thyroid-specific transcription factors control Hex promoter activity.

Authors:  Cinzia Puppin; Angela V D'Elia; Lucia Pellizzari; Diego Russo; Franco Arturi; Ivan Presta; Sebastiano Filetti; Clifford W Bogue; Lee A Denson; Giuseppe Damante
Journal:  Nucleic Acids Res       Date:  2003-04-01       Impact factor: 16.971

3.  Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype.

Authors:  Raphaelle Grifone; Christine Laclef; François Spitz; Soledad Lopez; Josiane Demignon; Jacques-Emmanuel Guidotti; Kiyoshi Kawakami; Pin-Xian Xu; Robert Kelly; Basil J Petrof; Dominique Daegelen; Jean-Paul Concordet; Pascal Maire
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272

4.  The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.

Authors:  Qing Xie; Ales Cvekl
Journal:  J Biol Chem       Date:  2011-10-13       Impact factor: 5.157

5.  The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation.

Authors:  Masakazu Kogawa; Koji Hisatake; Gerald J Atkins; David M Findlay; Yuichiro Enoki; Tsuyoshi Sato; Peter C Gray; Yukiko Kanesaki-Yatsuka; Paul H Anderson; Seiki Wada; Naoki Kato; Aya Fukuda; Shigehiro Katayama; Masafumi Tsujimoto; Tetsuya Yoda; Tatsuo Suda; Yasushi Okazaki; Masahito Matsumoto
Journal:  J Biol Chem       Date:  2013-08-29       Impact factor: 5.157

6.  Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.

Authors:  Elizabeth Charytonowicz; Igor Matushansky; Mireia Castillo-Martin; Todd Hricik; Carlos Cordon-Cardo; Mel Ziman
Journal:  Clin Transl Oncol       Date:  2011-03       Impact factor: 3.405

7.  Evaluation of PAX2 and PAX8 expression in salivary gland neoplasms.

Authors:  Randall T Butler; Megan A Alderman; Lester D R Thompson; Jonathan B McHugh
Journal:  Head Neck Pathol       Date:  2014-04-26

8.  Natural selection and molecular evolution in primate PAX9 gene, a major determinant of tooth development.

Authors:  Tiago V Pereira; Francisco M Salzano; Adrianna Mostowska; Wieslaw H Trzeciak; Andrés Ruiz-Linares; José A B Chies; Carmen Saavedra; Cleusa Nagamachi; Ana M Hurtado; Kim Hill; Dinorah Castro-de-Guerra; Wilson A Silva-Júnior; Maria-Cátira Bortolini
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-03       Impact factor: 11.205

9.  Modeling early Epstein-Barr virus infection in Drosophila melanogaster: the BZLF1 protein.

Authors:  Amy L Adamson; Natasha Wright; Dennis R LaJeunesse
Journal:  Genetics       Date:  2005-08-03       Impact factor: 4.562

10.  Molecular classification of rhabdomyosarcoma--genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group.

Authors:  Elai Davicioni; Michael J Anderson; Friedrich Graf Finckenstein; James C Lynch; Stephen J Qualman; Hiroyuki Shimada; Deborah E Schofield; Jonathan D Buckley; William H Meyer; Poul H B Sorensen; Timothy J Triche
Journal:  Am J Pathol       Date:  2009-01-15       Impact factor: 4.307
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