Literature DB >> 11750323

FTY720: dissection of membrane receptor-operated, stereospecific effects on cell migration from receptor-independent antiproliferative and apoptotic effects.

V Brinkmann1, C Wilt, C Kristofic, Z Nikolova, R P Hof, S Chen, R Albert, S Cottens.   

Abstract

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Year:  2001        PMID： 11750323     DOI： 10.1016/s0041-1345(01)02312-0

Source DB:  PubMed          Journal:  Transplant Proc        ISSN： 0041-1345            Impact factor:   1.066


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  12 in total

1.  Non-phosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2.

Authors:  Takashi Yoshino; Hiroko Tabunoki; Shigeo Sugiyama; Keitaro Ishii; Seung U Kim; Jun-Ichi Satoh
Journal:  Cell Mol Neurobiol       Date:  2011-04-26       Impact factor: 5.046

Review 2.  Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.

Authors:  Volker Brinkmann; Andreas Billich; Thomas Baumruker; Peter Heining; Robert Schmouder; Gordon Francis; Shreeram Aradhye; Pascale Burtin
Journal:  Nat Rev Drug Discov       Date:  2010-10-29       Impact factor: 84.694

3.  The role of sphingosine 1-phosphate in immunity and sepsis.

Authors:  Markus H Gräler
Journal:  Am J Clin Exp Immunol       Date:  2012-09-27

Review 4.  Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.

Authors:  Mirjam Schuchardt; Markus Tölle; Jasmin Prüfer; Markus van der Giet
Journal:  Br J Pharmacol       Date:  2011-07       Impact factor: 8.739

5.  FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes.

Authors:  Shaun M Honig; Shuang Fu; Xia Mao; Adam Yopp; Michael D Gunn; Gwendalyn J Randolph; Jonathan S Bromberg
Journal:  J Clin Invest       Date:  2003-03       Impact factor: 14.808

6.  The S1P1 receptor-selective agonist CYM-5442 reduces the severity of acute GVHD by inhibiting macrophage recruitment.

Authors:  Qiao Cheng; Shoubao Ma; Dandan Lin; Yu Mei; Huanle Gong; Lei Lei; Yuanyuan Chen; Ye Zhao; Bo Hu; Yan Wu; Xiao Yu; Lixiang Zhao; Haiyan Liu
Journal:  Cell Mol Immunol       Date:  2014-08-04       Impact factor: 11.530

7.  FTY720 prolongs clear corneal allograft survival with a differential effect on different lymphocyte populations.

Authors:  K Mayer; F Birnbaum; T Reinhard; A Reis; S Braunstein; F Claas; R Sundmacher
Journal:  Br J Ophthalmol       Date:  2004-07       Impact factor: 4.638

8.  The immunosuppressant FTY720 (fingolimod) enhances glycosaminoglycan depletion in articular cartilage.

Authors:  Martin H Stradner; Hannes Angerer; Thomas Ortner; Florentine C Fuerst; Daniela Setznagl; Marie-Luise Kremser; Josef Hermann; Winfried B Graninger
Journal:  BMC Musculoskelet Disord       Date:  2011-12-12       Impact factor: 2.362

9.  FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity.

Authors:  Dilruba Ahmed; Petra J de Verdier; Charlotta Ryk; Oscar Lunqe; Per Stål; Jenny Flygare
Journal:  Pharmacol Res Perspect       Date:  2015-08-19

10.  Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions.

Authors:  Peter Vogel; Michael S Donoviel; Robert Read; Gwenn M Hansen; Jill Hazlewood; Stephen J Anderson; Weimei Sun; Jonathan Swaffield; Tamas Oravecz
Journal:  PLoS One       Date:  2009-01-01       Impact factor: 3.240
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