Literature DB >> 11750317

FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines.

S Chen1, K B Bacon, G Garcia, R Liao, Z K Pan, S K Sullivan, H Nakano, A Matsuzawa, V Brinkmann, L Feng.   

Abstract

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Year:  2001        PMID： 11750317     DOI： 10.1016/s0041-1345(01)02306-5

Source DB:  PubMed          Journal:  Transplant Proc        ISSN： 0041-1345            Impact factor:   1.066


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  5 in total

1.  FTY720 markedly increases alloengraftment but does not eliminate host anti-donor T cells that cause graft rejection on its withdrawal.

Authors:  Patricia A Taylor; Ryan M Kelly; Nick D Bade; Michelle J Smith; Heather E Stefanski; Bruce R Blazar
Journal:  Biol Blood Marrow Transplant       Date:  2012-06-19       Impact factor: 5.742

2.  The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.

Authors:  Cornelia Halin; M Lucila Scimone; Roberto Bonasio; Jean-Marc Gauguet; Thorsten R Mempel; Elizabeth Quackenbush; Richard L Proia; Suzanne Mandala; Ulrich H von Andrian
Journal:  Blood       Date:  2005-05-03       Impact factor: 22.113

3.  Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720.

Authors:  Yong-Mi Kim; Teviah Sachs; Wannee Asavaroengchai; Roderick Bronson; Megan Sykes
Journal:  J Clin Invest       Date:  2003-03       Impact factor: 14.808

4.  FTY720 prolongs clear corneal allograft survival with a differential effect on different lymphocyte populations.

Authors:  K Mayer; F Birnbaum; T Reinhard; A Reis; S Braunstein; F Claas; R Sundmacher
Journal:  Br J Ophthalmol       Date:  2004-07       Impact factor: 4.638

Review 5.  FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system.

Authors:  Volker Brinkmann
Journal:  Br J Pharmacol       Date:  2009-10-08       Impact factor: 8.739
  5 in total

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