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Literature DB >> 11749350

Biocatalytic selective modifications of conventional nucleosides, carbocyclic nucleosides, and C-nucleosides.

M Ferrero¹, V Gotor.

Abstract

Entities: Chemical

Year: 2000 PMID： 11749350 DOI： 10.1021/cr000446y

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

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25 in total

1. Chemoenzymatic syntheses and anti-HIV-1 activity of glucose-nucleoside conjugates as prodrugs.

Authors: Tatiana Rodríguez-Pérez; Susana Fernández; Yogesh S Sanghvi; Mervi Detorio; Raymond F Schinazi; Vicente Gotor; Miguel Ferrero
Journal: Bioconjug Chem Date: 2010-11-15 Impact factor: 4.774

Review 2. Structural modifications of nucleosides in ionic liquids.

Authors: Vineet Kumar; Virinder S Parmar; Sanjay V Malhotra
Journal: Biochimie Date: 2010-02-21 Impact factor: 4.079

3. Synthesis of cyclopentanyl carbocyclic 5-fluorocytosine ((-)-5-fluorocarbodine) using a facially selective hydrogenation approach.

Authors: Jong Hyun Cho; Franck Amblard; Steven J Coats; Raymond F Schinazi
Journal: J Org Chem Date: 2012-12-26 Impact factor: 4.354

4. Scaleable processes for the synthesis of (-)-β-D-2,6-diaminopurine dioxolane (Amdoxovir, DAPD) and (-)-β-D-2-aminopurine dioxolane (APD).

Authors: Longhu Zhou; Steven J Coats; Hongwang Zhang; Shi Junxing; Drew R Bobeck; Raymond F Schinazi
Journal: Tetrahedron Date: 2012-05-16 Impact factor: 2.457

Biocatalytic selective modifications of conventional nucleosides, carbocyclic nucleosides, and C-nucleosides.

1. Chemoenzymatic syntheses and anti-HIV-1 activity of glucose-nucleoside conjugates as prodrugs.

Review 2. Structural modifications of nucleosides in ionic liquids.

3. Synthesis of cyclopentanyl carbocyclic 5-fluorocytosine ((-)-5-fluorocarbodine) using a facially selective hydrogenation approach.

4. Scaleable processes for the synthesis of (-)-β-D-2,6-diaminopurine dioxolane (Amdoxovir, DAPD) and (-)-β-D-2-aminopurine dioxolane (APD).

5. Acetoxy Meldrum's acid: a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation.

6. Syntheses of new spirocarbocyclic nucleoside analogs using iminonitroso Diels-Alder reactions.

7. Diastereoselective synthesis of a spironoraristeromycin using an acylnitroso Diels-Alder reaction.

8. Discovery of New Acid Ceramidase-Targeted Acyclic 5-Alkynyl and 5-Heteroaryl Uracil Nucleosides.

9. Highly efficient O-glycosylations with p-tolyl thioribosides and p-TolSOTf.

10. Enlarging the substrate portfolio of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius.