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Literature DB >> 11748207

Production of prostaglandins and leukotrienes by pathogenic fungi.

Mairi C Noverr¹, Galen B Toews, Gary B Huffnagle.

Abstract

These studies demonstrate that pathogenic fungi (dermatophytic, subcutaneous, and systemic) have the ability to produce eicosanoids both from simple metabolites and from arachidonic acid. Host-derived eicosanoids have been previously demonstrated to enhance fungal colonization and atopic disease development. Thus, fungus-derived eicosanoids represent a potential class of novel virulence factors.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2002 PMID： 11748207 PMCID： PMC127633 DOI： 10.1128/IAI.70.1.400-402.2002

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

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