Literature DB >> 11747906

Generation of a selective 5-HT3B subunit-recognising polyclonal antibody; identification of immunoreactive cells in rat hippocampus.

S A Monk1, K Desai, C A Brady, J M Williams, L Lin, A Princivalle, A G Hope, N M Barnes.   

Abstract

The present study generated a polyclonal antibody (AP86/3) that recognises a peptide sequence of the h5-HT(3B) receptor subunit. Western blot analysis of homogenates prepared from cell lines expressing either homomeric (h5-HT(3A)) or heteromeric (h5-HT(3A/3B)) receptors, as well as immunocytochemical studies with the same cell lines, indicated that AP86/3 recognised, selectively, the 5-HT(3B) subunit. Immunohistochemical labelling was also apparent in cells in the rat hippocampus that displayed the distribution and morphology of interneurones.

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Year:  2001        PMID： 11747906     DOI： 10.1016/s0028-3908(01)00153-8

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN： 0028-3908            Impact factor:   5.250


  11 in total

1.  Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization.

Authors:  Sterling N Sudweeks; Johannes A van Hooft; Jerrel L Yakel
Journal:  J Physiol       Date:  2002-11-01       Impact factor: 5.182

2.  Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols.

Authors:  Renna Stevens; Dirk Rüsch; Ken Solt; Douglas E Raines; Paul A Davies
Journal:  J Pharmacol Exp Ther       Date:  2005-04-14       Impact factor: 4.030

3.  Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT3 receptor expression via acetate production.

Authors:  Yogesh Bhattarai; Bradley A Schmidt; David R Linden; Eric D Larson; Madhusudan Grover; Arthur Beyder; Gianrico Farrugia; Purna C Kashyap
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2017-04-13       Impact factor: 4.052

4.  Inhibition of human 5-HT(3A) and 5-HT(3AB) receptors by etomidate, propofol and pentobarbital.

Authors:  Dirk Rüsch; Hans A Braun; Hinnerk Wulf; Anika Schuster; Douglas E Raines
Journal:  Eur J Pharmacol       Date:  2007-07-13       Impact factor: 4.432

Review 5.  Therapeutics of 5-HT3 receptor antagonists: current uses and future directions.

Authors:  Tina K Machu
Journal:  Pharmacol Ther       Date:  2011-02-26       Impact factor: 12.310

Review 6.  5-HT3 receptors.

Authors:  A J Thompson; S C R Lummis
Journal:  Curr Pharm Des       Date:  2006       Impact factor: 3.116

7.  Improvements in hippocampal-dependent learning and decremental attention in 5-HT(3) receptor overexpressing mice.

Authors:  Amber V Harrell; Andrea M Allan
Journal:  Learn Mem       Date:  2003 Sep-Oct       Impact factor: 2.460

Review 8.  The 5-HT3 receptor--the relationship between structure and function.

Authors:  Nicholas M Barnes; Tim G Hales; Sarah C R Lummis; John A Peters
Journal:  Neuropharmacology       Date:  2008-08-12       Impact factor: 5.250

Review 9.  3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors.

Authors:  Anders A Jensen; Paul A Davies; Hans Bräuner-Osborne; Karen Krzywkowski
Journal:  Trends Pharmacol Sci       Date:  2008-09       Impact factor: 14.819

Review 10.  5-HT(3) receptors.

Authors:  Sarah C R Lummis
Journal:  J Biol Chem       Date:  2012-10-04       Impact factor: 5.157
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