Literature DB >> 11746848

Studies on the hypoglycaemic activity of Punica granatum seed in streptozotocin induced diabetic rats.

A K Das1, S C Mandal, S K Banerjee, S Sinha, B P Saha, M Pal.   

Abstract

The hypoglycaemic activity of Punica granatum Linn. (Family Punicaceae) seed extract on rats made diabetic by streptozotocin (STZ) was investigated. The methanol extract of the seed at doses of 300 and 600 mg/kg, and chlorpropamide 200 mg/kg was administered to STZ diabetic rats. The seed extract (150, 300 and 600 mg/kg, orally) caused a significant reduction of blood glucose levels in STZ induced diabetic rats by 47% and 52%, respectively, at the end of 12 h. Copyright 2001 John Wiley & Sons, Ltd.

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Year:  2001        PMID： 11746848     DOI： 10.1002/ptr.740

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  10 in total

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  10 in total

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