| Literature DB >> 11746787 |
A J A De Louw1, W D J Van De Berg, J De Vente, C E Blanco, A W D Gavilanes, H P J Steinbusch, H W M Steinbusch, J Troost, J S H Vles.
Abstract
We investigated developmental apoptosis in the white matter of the cervical spinal cord at postnatal days 2, 5, and 8. Apoptotic cells were labeled using TUNEL and caspase-3 immunostaining. Apoptotic cells were diffusely distributed throughout the white matter of the spinal cord. The total amount of apoptotic cells in the cervical spinal cord white matter was related to postnatal age, with the lowest at P2 (mean 7.9, SD 5.6) and the highest at P8 (mean 109, SD 21.4). Using double immunostaining for ED-1 and O4, apoptotic cells were identified as microglia and oligodendrocytes. Copyright 2002 Wiley-Liss, Inc.Entities:
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Year: 2002 PMID： 11746787 DOI： 10.1002/glia.1130
Source DB: PubMed Journal: Glia ISSN： 0894-1491 Impact factor: 7.452