Literature DB >> 11745763

Quantification of suppression of bitterness using an electronic tongue.

S Takagi1, K Toko, K Wada, T Ohki.   

Abstract

Phospholipids, such as phosphatidic acid, suppress bitter taste without affecting other taste qualities. In the present study, we detected and quantified this suppression effect with an electronic tongue whose transducer is composed of several kinds of lipid/polymer membranes with different characteristics. We measured a phospholipid cocktail and various kinds of taste substances with five basic taste qualities. The responses to quinine hydrochloride and L-tryptophan, which have a bitter taste, were reduced as the phospholipid concentration was increased, and the responses to the other taste substances were not affected by the phospholipids, as with the human sensation test. Furthermore, the change of bitter intensity caused by phospholipid was quantified by principal component analysis and the tau scale, which expresses the relationship between taste intensity and taste substance concentration. The results are compared with those of the human sensory test and discussed. Copyright 2001 Wiley-Liss, Inc. and the American Pharmaceutical Association

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Year:  2001        PMID: 11745763     DOI: 10.1002/jps.1155

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  6 in total

1.  An electronic tongue: evaluation of the masking efficacy of sweetening and/or flavoring agents on the bitter taste of epinephrine.

Authors:  Ousama Rachid; F Estelle R Simons; Mutasem Rawas-Qalaji; Keith J Simons
Journal:  AAPS PharmSciTech       Date:  2010-03-30       Impact factor: 3.246

Review 2.  Phospholipids and lipid-based formulations in oral drug delivery.

Authors:  Gert Fricker; Torsten Kromp; Armin Wendel; Alfred Blume; Jürgen Zirkel; Herbert Rebmann; Constanze Setzer; Ralf-Olaf Quinkert; Frank Martin; Christel Müller-Goymann
Journal:  Pharm Res       Date:  2010-04-22       Impact factor: 4.200

3.  Quantitative prediction of the bitterness suppression of elemental diets by various flavors using a taste sensor.

Authors:  Yohko Miyanaga; Naoko Inoue; Ayako Ohnishi; Emi Fujisawa; Maki Yamaguchi; Takahiro Uchida
Journal:  Pharm Res       Date:  2003-12       Impact factor: 4.200

Review 4.  Advanced taste sensors based on artificial lipids with global selectivity to basic taste qualities and high correlation to sensory scores.

Authors:  Yoshikazu Kobayashi; Masaaki Habara; Hidekazu Ikezazki; Ronggang Chen; Yoshinobu Naito; Kiyoshi Toko
Journal:  Sensors (Basel)       Date:  2010-04-08       Impact factor: 3.576

5.  Evaluation of the Bitterness of Traditional Chinese Medicines using an E-Tongue Coupled with a Robust Partial Least Squares Regression Method.

Authors:  Zhaozhou Lin; Qiao Zhang; Ruixin Liu; Xiaojie Gao; Lu Zhang; Bingya Kang; Junhan Shi; Zidan Wu; Xinjing Gui; Xuelin Li
Journal:  Sensors (Basel)       Date:  2016-01-25       Impact factor: 3.576

6.  Improved Durability and Sensitivity of Bitterness-Sensing Membrane for Medicines.

Authors:  Xiao Wu; Hideya Onitake; Zhiqin Huang; Takeshi Shiino; Yusuke Tahara; Rui Yatabe; Hidekazu Ikezaki; Kiyoshi Toko
Journal:  Sensors (Basel)       Date:  2017-11-04       Impact factor: 3.576

  6 in total

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