Literature DB >> 1174464

Albinism in Nigeria. A clinical and social study.

A N Okoro.   

Abstract

A study of 1000 Nigerian albinos, all of Negro stock, showed various types of albinism with their different modes of transmission--oculocutaneous, ocular and cutaneous. The much higher incidence among the more settled communities in the south, compared with the more nomadic communities in the north, may be related to greater inbreeding tendencies in the south. The sun and society are hostile to the albinos. Under the tropical sunshine, their melanin-deficient skin develops wrinkles, lentigines, actinic keratoses and epitheliomata from which they may die in early adult life or in middle age. Myopia and other ocular defects retard the progress of many albinos in school and they eventually drop out to seek disastrous menial outdoor occupations. Registering albinos early in life, assuring their families that albino defects are confined to the skin and eyes, advising on protective clothing and sun-screening agents, correcting myopia, assisting with indooor occupations, and early treatment of actinic keratoses and skin cancer should help many albinos to attain social acceptance and a ripe old age.

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Year:  1975        PMID: 1174464

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  37 in total

1.  Locally advanced skin cancer in an albino: a treatment dilemma.

Authors:  G Mapurisa; L Masamba
Journal:  Malawi Med J       Date:  2010-12       Impact factor: 0.875

2.  Oculocutaneous albinism type 2 (OCA2) with homozygous 2.7-kb deletion of the P gene and sickle cell disease in a Cameroonian family. Identification of a common TAG haplotype in the mutated P gene.

Authors:  Robert Aquaron; Nadem Soufir; Jean-Louis Bergé-Lefranc; Catherine Badens; Frederic Austerlitz; Bernard Grandchamp
Journal:  J Hum Genet       Date:  2007-09-01       Impact factor: 3.172

3.  Distribution of oculocutaneous albinism in Zimbabwe.

Authors:  P M Lund
Journal:  J Med Genet       Date:  1996-08       Impact factor: 6.318

4.  Nevoid malignant melanoma in an albino woman.

Authors:  F Binesh; A Akhavan; H Navabii
Journal:  BMJ Case Rep       Date:  2010-12-06

5.  DNA damage enhances melanogenesis.

Authors:  M S Eller; K Ostrom; B A Gilchrest
Journal:  Proc Natl Acad Sci U S A       Date:  1996-02-06       Impact factor: 11.205

6.  Advanced skin cancer in Tanzanian albinos: preliminary observations.

Authors:  G A Alexander; U K Henschke
Journal:  J Natl Med Assoc       Date:  1981-11       Impact factor: 1.798

7.  Skin cancers in albinos in a teaching Hospital in eastern Nigeria - presentation and challenges of care.

Authors:  Kingsley O Opara; Bernard C Jiburum
Journal:  World J Surg Oncol       Date:  2010-08-25       Impact factor: 2.754

8.  Prevalence and profile of ophthalmic disorders in oculocutaneous albinism: a field report from South-Eastern Nigeria.

Authors:  N N Udeh; B I Eze; S N Onwubiko; O C Arinze; E N Onwasigwe; R E Umeh
Journal:  J Community Health       Date:  2014-12

Review 9.  Was skin cancer a selective force for black pigmentation in early hominin evolution?

Authors:  Mel Greaves
Journal:  Proc Biol Sci       Date:  2014-02-26       Impact factor: 5.349

10.  Oculocutaneous albinism: identifying and overcoming barriers to vision care in a Nigerian population.

Authors:  N N Udeh; B I Eze; S N Onwubiko; O C Arinze; E N Onwasigwe; R E Umeh
Journal:  J Community Health       Date:  2014-06
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