Literature DB >> 11744010

Negative inotropic mediators released from the heart after myocardial ischaemia-reperfusion.

Verena Stangl1, Gert Baumann, Karl Stangl, Stephan B Felix.   

Abstract

The heart responds to ischaemic stimuli with release of negative inotropic mediators such as cytokines, platelet-activating factor, oxygen free radicals, arachidonic acids, nitric oxide, adenosine, and still unidentified "cardiodepressant factors" that modulate myocardial performance via autocrine and paracrine coupling. This review summarises experimental and clinical data on the role of negative inotropic mediators that are released from cardiac cells (including cardiomyocytes, endothelial cells, and resident mast cells) after myocardial ischaemia-reperfusion.

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Year:  2002        PMID： 11744010     DOI： 10.1016/s0008-6363(01)00420-5

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN： 0008-6363            Impact factor:   10.787


  12 in total

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Journal:  J Cell Mol Med       Date:  2013-11-01       Impact factor: 5.310
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