Literature DB >> 1174039

[Anti-phalloidine activity of the silymarins silybine and disilybine].

V G Vogel, W Trost.   

Abstract

Originating from silybin, a phenylchromanone from Silybum marianum (L.) Gaertn., a dimer -- disilybin -- was prepared. Disilybin exhibits a phalloidin antagonistic activity at least 10 times that of silybin with regards to a dose of the same weight.

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Year:  1975        PMID: 1174039

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  3 in total

1.  Antagonistic effects against single lethal doses of Amanita phalloides.

Authors:  G L Floersheim
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-05       Impact factor: 3.000

2.  Protection by phalloidin against lethal doses of phalloidin.

Authors:  G L Floersheim
Journal:  Agents Actions       Date:  1976-07

3.  Anti-phalloidine and anti-alpha-amanitine action of silybin in comparison with compounds similar to structural parts of silybin.

Authors:  W Trost; G Halbach
Journal:  Experientia       Date:  1978-08-15
  3 in total

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