| Literature DB >> 11739836 |
D Stoffers1, H W Berendse, J B Deijen, E C Wolters.
Abstract
Perseveration in the generation of random motor behavior was examined by means of the Vienna perseverance task in groups of de novo (n = 18) and treated (n = 18) patients with early PD, and in control subjects (n = 18). In comparison with control subjects, both the de novo and treated patients with PD were relatively unable to generate random motor sequences, indicating a decreased ability to switch cortical behavioral programs in PD. An impairment of random motor generation appears to be a very early feature of PD.Entities:
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Year: 2001 PMID: 11739836 DOI: 10.1212/wnl.57.11.2111
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910