| Literature DB >> 11738574 |
Hiromasa Hashimoto1, Kimiya Maeda, Koichi Ozawa, Jun-ichi Haruta, Korekiyo Wakitani.
Abstract
A series of 4-aryl/cycloalkyl-5-phenyloxazole derivatives was synthesized and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2) and cyclooxygenase-1 (COX-1). These compounds were found to be potent and selective COX-2 inhibitors.Entities:
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Year: 2002 PMID： 11738574 DOI： 10.1016/s0960-894x(01)00670-9
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823