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Literature DB >> 11737938

What does a worm want with 20,000 genes?

Abstract

The number of genes predicted for the Caenorhabditis elegans genome is remarkably high: approximately 20,000, if both protein-coding and RNA-coding genes are counted. This article discusses possible explanations for such a high value.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
RNA, Helminth

Year: 2001 PMID： 11737938 PMCID： PMC138976 DOI： 10.1186/gb-2001-2-11-comment2008

Source DB: PubMed Journal: Genome Biol ISSN： 1474-7596 Impact factor: 13.583

28 in total

Review 1. Noncoding RNA genes.

Authors: S R Eddy
Journal: Curr Opin Genet Dev Date: 1999-12 Impact factor: 5.578

2. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference.

Authors: A G Fraser; R S Kamath; P Zipperlen; M Martinez-Campos; M Sohrmann; J Ahringer
Journal: Nature Date: 2000-11-16 Impact factor: 49.962

3. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III.

Authors: P Gönczy; C Echeverri; K Oegema; A Coulson; S J Jones; R R Copley; J Duperon; J Oegema; M Brehm; E Cassin; E Hannak; M Kirkham; S Pichler; K Flohrs; A Goessen; S Leidel; A M Alleaume; C Martin; N Ozlü; P Bork; A A Hyman
Journal: Nature Date: 2000-11-16 Impact factor: 49.962

4. Digging for dead genes: an analysis of the characteristics of the pseudogene population in the Caenorhabditis elegans genome.

Authors: P M Harrison; N Echols; M B Gerstein
Journal: Nucleic Acids Res Date: 2001-02-01 Impact factor: 16.971

Review 5. Caenorhabditis elegans for the study of host-pathogen interactions.

Authors: C L Kurz; J J Ewbank
Journal: Trends Microbiol Date: 2000-03 Impact factor: 17.079

6. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans.

Authors: B J Reinhart; F J Slack; M Basson; A E Pasquinelli; J C Bettinger; A E Rougvie; H R Horvitz; G Ruvkun
Journal: Nature Date: 2000-02-24 Impact factor: 49.962

7. High-throughput isolation of Caenorhabditis elegans deletion mutants.

Authors: L X Liu; J M Spoerke; E L Mulligan; J Chen; B Reardon; B Westlund; L Sun; K Abel; B Armstrong; G Hardiman; J King; L McCague; M Basson; R Clover; C D Johnson
Journal: Genome Res Date: 1999-09 Impact factor: 9.043

8. A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans.

Authors: J Hodgkin; P E Kuwabara; B Corneliussen
Journal: Curr Biol Date: 2000 Dec 14-28 Impact factor: 10.834

9. The large srh family of chemoreceptor genes in Caenorhabditis nematodes reveals processes of genome evolution involving large duplications and deletions and intron gains and losses.

Authors: H M Robertson
Journal: Genome Res Date: 2000-02 Impact factor: 9.043

10. Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans.

Authors: L D Marroquin; D Elyassnia; J S Griffitts; J S Feitelson; R V Aroian
Journal: Genetics Date: 2000-08 Impact factor: 4.562

11 in total

Review 1. Dopamine signaling architecture in Caenorhabditis elegans.

Authors: Paul W McDonald; Tammy Jessen; Julie R Field; Randy D Blakely
Journal: Cell Mol Neurobiol Date: 2006-05-25 Impact factor: 5.046

Review 2. Revising the standard wisdom of C. elegans natural history: ecology of longevity.

Authors: E P Caswell-Chen; J Chen; E E Lewis; G W Douhan; S A Nadler; J R Carey
Journal: Sci Aging Knowledge Environ Date: 2005-10-05

3. The role of self-organization in developmental evolution.

Authors: Joseph E Hannon Bozorgmehr
Journal: Theory Biosci Date: 2014-04-16 Impact factor: 1.919

4. The molecular phylogeny of a nematode-specific clade of heterotrimeric G-protein alpha-subunit genes.

Authors: Damien M O'Halloran; David A Fitzpatrick; Grace P McCormack; James O McInerney; Ann M Burnell
Journal: J Mol Evol Date: 2006-06-16 Impact factor: 2.395

5. fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen.

Authors: David S Fay; Sean Keenan; Min Han
Journal: Genes Dev Date: 2002-02-15 Impact factor: 11.361

Review 6. How early media exposure may affect cognitive function: A review of results from observations in humans and experiments in mice.

Authors: Dimitri A Christakis; Julian S Benedikt Ramirez; Susan M Ferguson; Shilpa Ravinder; Jan-Marino Ramirez
Journal: Proc Natl Acad Sci U S A Date: 2018-10-02 Impact factor: 11.205