Literature DB >> 11736881

Opioid analgesic prescribing and use - an audit of analgesic prescribing by general practitioners and The Multidisciplinary Pain Centre at Royal Brisbane Hospital.

L M Nissen1, S E Tett, T Cramond, B Williams, M T Smith.   

Abstract

AIMS: This study evaluated the use of and need for opioids in patients attending the Multidisciplinary Pain Centre at the Royal Brisbane Hospital (RBH).
METHODS: All consecutive in-patient admissions in 1998 were reviewed. A 10-point scoring system based on the World Health Organization (WHO) analgesic ladder was devised to facilitate comparison of analgesic prescribing on admission and at the time of discharge. A conversion table was used to standardize opioid analgesic doses to an oral morphine equivalent.
RESULTS: Of the 370 patients reviewed, 233 (81%) were by their general practitioners. Records of 288 (78%) were available for full review and 270 (94%) of these had noncancer pain. On admission, 239 (83%) were taking an opioid analgesic, with 135 (47%) taking strong opioids (e.g. morphine, oxycodone, methadone). There was a significant decrease in the mean total daily oral morphine equivalent prescribed on discharge 36.9 mg (95% CI: 33.4, 40.4) compared with that on admission 88.7 mg (95% CI: 77.6, 99.8) (P < 0.001). There was a significant decrease (P < 0.05) in the proportion of patients taking a primary opioid on discharge 153 (58%) compared with admission 239 (83%), although the proportion of patients taking a strong opioid on discharge 150 (52%) compared with admission 135 (47%) was not significantly different (P > 0.05). The proportion of patients taking a laxative showed a significant increase on discharge 110 (73%) compared with admission 38 (28%) (P < 0.05).
CONCLUSIONS: Our analgesic prescribing scoring system and opioid conversion table have the potential to be developed further as tools for assessing opioid analgesic prescribing. The significant decrease in total daily oral morphine equivalents signifies the value of prescribing in accordance with the WHO analgesic ladder, and the necessity of general practitioner education. The management of chronic pain is complex, and it requires interventions additional to pharmacological therapy. Evaluation by a multidisciplinary team, coupled with experience in and an understanding of analgesic prescribing and rehabilitation provides an effective basis for improving the management of patients with chronic pain.

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Year:  2001        PMID: 11736881      PMCID: PMC2014564          DOI: 10.1046/j.0306-5251.2001.01502.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  12 in total

Review 1.  Role of opioids in chronic non-cancer pain.

Authors:  A R Molloy; M K Nicholas; M J Cousins
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3.  Australian trends in opioid prescribing for chronic non-cancer pain, 1986-1996.

Authors:  J R Bell
Journal:  Med J Aust       Date:  1997-07-07       Impact factor: 7.738

4.  The relation between pain beliefs, negative thoughts, and psychosocial functioning in chronic pain patients.

Authors:  M W Stroud; B E Thorn; M P Jensen; J L Boothby
Journal:  Pain       Date:  2000-02       Impact factor: 6.961

5.  Treatment outcome of chronic non-malignant pain patients managed in a danish multidisciplinary pain centre compared to general practice: a randomised controlled trial.

Authors:  N Becker; P Sjøgren; P Bech; A K Olsen; J Eriksen
Journal:  Pain       Date:  2000-02       Impact factor: 6.961

6.  Outcomes of an educational-outreach service for community medical practitioners: non-steroidal anti-inflammatory drugs.

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7.  Physician attitudes and practice in cancer pain management. A survey from the Eastern Cooperative Oncology Group.

Authors:  J H Von Roenn; C S Cleeland; R Gonin; A K Hatfield; K J Pandya
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8.  Direct conversion from oral morphine to transdermal fentanyl: a multicenter study in patients with cancer pain.

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Journal:  Pain       Date:  1996-03       Impact factor: 6.961

9.  Drug utilization review in ambulatory settings: state of the science and directions for outcomes research.

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10.  Characteristics of referrals to an inpatient hospice and a survey of general practitioner perceptions of palliative care.

Authors:  D A Seamark; C Lawrence; J Gilbert
Journal:  J R Soc Med       Date:  1996-02       Impact factor: 18.000

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5.  Multidisciplinary care for opioid dose reduction in patients with chronic non-cancer pain: A systematic realist review.

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6.  Prescribing and Administration of Opioid Analgesics in Residents of Aged Care Facilities.

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7.  Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain: systematic review and meta-analysis.

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Review 8.  A review of trial and real-world data applying elements of a realist approach to identify behavioural mechanisms supporting practitioners to taper opioids.

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  8 in total

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