Literature DB >> 11735565

Ketone-DNA: a versatile postsynthetic DNA decoration platform.

S Dey1, T L Sheppard.   

Abstract

[reaction: see text] A general strategy for the functional diversification of DNA oligonucleotides under physiological conditions was developed. We describe the synthesis of DNA molecules bearing ketone ports (ketone-DNA) and the efficient postsynthetic decoration of ketone-DNA with structurally diverse aminooxy compounds.

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Year:  2001        PMID： 11735565     DOI： 10.1021/ol016626r

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).

Authors:  Plamen P Christov; Katya V Petrova; Ganesh Shanmugam; Ivan D Kozekov; Albena Kozekova; F Peter Guengerich; Michael P Stone; Carmelo J Rizzo
Journal:  Chem Res Toxicol       Date:  2010-08-16       Impact factor: 3.739

2.  A novel method for direct site-specific radiolabeling of peptides using [18F]FDG.

Authors:  Mohammad Namavari; Zhen Cheng; Rong Zhang; Abhijit De; Jelena Levi; Joshua K Hoerner; Shahriar S Yaghoubi; Faisal A Syud; Sanjiv S Gambhir
Journal:  Bioconjug Chem       Date:  2009-03-18       Impact factor: 4.774

3.  Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA.

Authors:  Nico Rublack; Hien Nguyen; Bettina Appel; Danilo Springstubbe; Denise Strohbach; Sabine Müller
Journal:  J Nucleic Acids       Date:  2011-10-12

4.  Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2'-deoxyuridines and their application in DNA triplex formation.

Authors:  John A Brazier; Takayuki Shibata; John Townsley; Brian F Taylor; Elaine Frary; Nicholas H Williams; David M Williams
Journal:  Nucleic Acids Res       Date:  2005-03-03       Impact factor: 16.971
  4 in total

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