| Literature DB >> 11733056 |
Abstract
Two recent studies illustrate the ability of the Mre11/Rad50 DNA repair complex to bind and connect DNA ends. Specific stimulation of DNA ligase IV-mediated end-joining by Mre11 complexes from S. cerevisiae suggests the possibility of a direct role in nonhomologous end-joining in eukaryotic cells.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11733056 DOI: 10.1016/s0092-8674(01)00591-8
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582