Kaposi's sarcoma of genitourinary tract.

Kaposi's sarcoma of the external genitalia is rare. Four cases with the initial lesion on the glans penis and 13 cases with secondary involvement of the external genitalia are presented. A high association between Kaposi's sarcoma and malignant lymphoma is noted. The natural history is one of multiple recurrences in the immediate vicinity of the primary site or at distant locations at varying time intervals. Wide margin electron beam irradiation is the recommended treatment. A variety of chemotherapeutic agents also have produced favorable responses; yet prognosis for cure is poor because of the generalized nature of the disease--the course of which is nevertheless often prolonged.