Literature DB >> 11732146

Respiratory rate as a predictor of positive lung aspirates in young Gambian children with lobar pneumonia.

A G Falade1, R A Adegbola, E K Mulholland, B M Greenwood.   

Abstract

Clinical predictors of a positive bacterial culture from lung aspirate or blood culture were investigated in 90 children under 5 years of age with lobar pneumonia on whom both lung aspiration and blood culture were performed. Of the 66 children with a respiratory rate of > or = 50 breaths/min, 35 (53%) had positive bacterial lung aspirates compared with only five (21.7%) of 23 children with a respiratory rate of < 50 breaths/min (odds ratio [OR] 4.06, 95% confidence interval [CI] 1.24-15.46, p = 0.02). Of the 41 children with positive lung aspirates, 31 (76%) had negative blood cultures. In contrast with children with positive lung aspirates, there were no clinical predictors of a positive blood culture. A respiratory rate of > or = 50 breaths/min in children with radiological evidence of lobar pneumonia would support lung aspiration as a positive result is significantly more likely than in children with a lower respiratory rate.

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Year:  2001        PMID: 11732146     DOI: 10.1080/07430170120093472

Source DB:  PubMed          Journal:  Ann Trop Paediatr        ISSN: 0272-4936


  2 in total

1.  Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study.

Authors:  James A Berkley; Kathryn Maitland; Isaiah Mwangi; Caroline Ngetsa; Saleem Mwarumba; Brett S Lowe; Charles R J C Newton; Kevin Marsh; J Anthony G Scott; Mike English
Journal:  BMJ       Date:  2005-03-29

2.  Discovery and validation of biomarkers to guide clinical management of pneumonia in African children.

Authors:  Honglei Huang; Readon C Ideh; Evelyn Gitau; Marie L Thézénas; Muminatou Jallow; Bernard Ebruke; Osaretin Chimah; Claire Oluwalana; Henri Karanja; Grant Mackenzie; Richard A Adegbola; Dominic Kwiatkowski; Benedikt M Kessler; James A Berkley; Stephen R C Howie; Climent Casals-Pascual
Journal:  Clin Infect Dis       Date:  2014-04-02       Impact factor: 9.079

  2 in total

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