Literature DB >> 11731117

Analgesic sesquiterpene dilactone from Mikania cordata.

M Ahmed1, M T Rahman, M Alimuzzaman, J A Shilpi.   

Abstract

The crude extract of Mikania cordata (1 and 3 g/kg, p.o.) and deoxymikanolide (1) (10 mg/kg, p.o.) significantly inhibited acetic acid-induced writhing in mice. Three other sesquiterpene dilactones isolated from the same plant, namely mikanolide, dihydromikanolide and scandenolide, did not show significant analgesic activity.

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Year:  2001        PMID: 11731117     DOI: 10.1016/s0367-326x(01)00318-5

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  4 in total

1.  Analgesic activity and acute toxicity study of Semecarpus anacardium stem bark extracts using mice.

Authors:  G M Lingaraju; H Joy Hoskeri; V Krishna; P Suresh Babu
Journal:  Pharmacognosy Res       Date:  2011-01

2.  Evaluation of anti-nociceptive, anti-inflammatory and antipyretic potential of Mikania cordata (Burm. f.) Robinson in experimental animal model.

Authors:  Shah Alam Siddiqui; Atiqur Rahman; M Oliur Rahman; Mohammad Ahsanul Akbar; A S Shamsur Rouf; Mohammad Ajmal Ali; Fahad M A Al-Hemaid; Mohammad Abul Farah
Journal:  Saudi J Biol Sci       Date:  2018-02-13       Impact factor: 4.219

3.  Design, Synthesis, and Antileukemic Evaluation of a Novel Mikanolide Derivative Through the Ras/Raf/MEK/ERK Pathway.

Authors:  Qing Rao; Kaiqiang Xie; Krishnapriya M Varier; Lei Huang; Jingrui Song; Jue Yang; Jianfei Qiu; Yubing Huang; Yan Li; Babu Gajendran; Yanmei Li; Sheng Liu
Journal:  Front Pharmacol       Date:  2022-05-20       Impact factor: 5.988

4.  Antimicrobial constituents of the leaves of Mikania micrantha H. B. K.

Authors:  Yan Li; Jun Li; Yuan Li; Xia-xia Wang; Ao-cheng Cao
Journal:  PLoS One       Date:  2013-10-02       Impact factor: 3.240

  4 in total

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