Literature DB >> 11731011

Increase of tyrosine hydroxylase and dopamine transporter mRNA levels in ventral tegmental area of male mice under influence of repeated aggression experience.

M L Filipenko1, O V Alekseyenko, A G Beilina, T P Kamynina, N N Kudryavtseva.   

Abstract

Tyrosine hydroxylase (TH) and dopamine transporter (DAT) mRNA levels in the ventral tegmental area (VTA) of midbrain were measured by multiplex RT-PCR in male mice with repeated experience of social victories (winners) and social defeats (losers) in 10 daily agonistic confrontations. Two independent experiments revealed enhanced TH and DAT mRNA levels in VTA of the winners in comparison with the losers and controls (animals after 5 days of individual housing). A positive correlation between DAT and TH mRNA levels was shown.

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Year:  2001        PMID： 11731011     DOI： 10.1016/s0169-328x(01)00270-4

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  22 in total

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