Literature DB >> 1173100

Physostigmine salicylate in the treatment of tricyclic antidepressant overdosage.

R W Newton.   

Abstract

Following intravenous administration of physostigmine salicylate for tricyclic antidepressant poisoning in 21 patients, convulsions occurred in two patients, and severe cholinergic manifestations occurred in two others. Because of these untoward effects and the very short duration of its beneficial action, it is very doubtful that physostigmine has any place in the routine management of tricyclic antidepressant poisoning.

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Year:  1975        PMID： 1173100

Source DB:  PubMed          Journal:  JAMA        ISSN： 0098-7484            Impact factor:   56.272


  15 in total

1.  Letter: Neostigmine methysulfate in the treatment of cardiac arryhthmia induced by perphenazine-amitriptyline.

Authors:  C W Raymond
Journal:  Can Med Assoc J       Date:  1976-01-24       Impact factor: 8.262

Review 2.  Clinical features, pathogenesis and management of drug-induced seizures.

Authors:  G Zaccara; G C Muscas; A Messori
Journal:  Drug Saf       Date:  1990 Mar-Apr       Impact factor: 5.606

3.  Adverse effects of physostigmine.

Authors:  A Houghton
Journal:  Can Anaesth Soc J       Date:  1977-07

4.  Acute poisoning: an update.

Authors:  C W Raymond
Journal:  Can Med Assoc J       Date:  1977-08-20       Impact factor: 8.262

Review 5.  Adverse Effects of Physostigmine.

Authors:  Ann M Arens; Tom Kearney
Journal:  J Med Toxicol       Date:  2019-02-11

6.  Effect of respiratory alkalosis in tricyclic antidepressant overdose.

Authors:  H A Bessen; J T Niemann; R J Haskell; R J Rothstein
Journal:  West J Med       Date:  1983-09

Review 7.  Antidepressant overdosage.

Authors:  P Crome
Journal:  Drugs       Date:  1982-06       Impact factor: 9.546

8.  Bicarbonate therapy for dysrhythmia and hypotension in tricyclic antidepressant overdose.

Authors:  J R Hoffman; C R McElroy
Journal:  West J Med       Date:  1981-01

Review 9.  Current antidepressant drugs: their clinical use.

Authors:  L E Hollister
Journal:  Drugs       Date:  1981-08       Impact factor: 9.546

Review 10.  Poisoning due to tricyclic antidepressant overdosage. Clinical presentation and treatment.

Authors:  P Crome
Journal:  Med Toxicol       Date:  1986 Jul-Aug
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