Literature DB >> 11730875

Taraxastane-type triterpenoids from Saussurea petrovii.

J Dai1, C Zhao, Q Zhang, Z L Liu, R Zheng, L Yang.   

Abstract

Two taraxastane triterpenoids, i.e. taraxast-20-ene-3beta,30-diol (1) and 20alpha,21alpha-epoxy-taraxastane-3beta,22alpha-diol (2), as well as four known triterpenes taraxast-20(30)ene-3beta,21alpha-diol (3), taraxast-20(30)-ene-3beta-ol (4), taraxast-20-ene-3beta-ol (5) and taraxastane-3beta,20alpha-diol (6) were isolated from the Chinese medicinal plant Saussurea petrovii. Their structures were elucidated by spectroscopic methods. These compounds, especially 1 and 2, exhibit significant antitumor and antibacterial activity.

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Year:  2001        PMID: 11730875     DOI: 10.1016/s0031-9422(01)00397-1

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  3 in total

1.  Taraxasterol suppresses the growth of human liver cancer by upregulating Hint1 expression.

Authors:  Tianhao Bao; Yang Ke; Yifan Wang; Weiwei Wang; Yuehua Li; Yan Wang; Xiang Kui; Qixin Zhou; Han Zhou; Cheng Zhang; Dongming Zhou; Lin Wang; Chunjie Xiao
Journal:  J Mol Med (Berl)       Date:  2018-05-27       Impact factor: 4.599

2.  Network pharmacology-based identification of the antitumor effects of taraxasterol in gastric cancer.

Authors:  Wei Chen; Jingwei Li; Chen Li; Hui-Ning Fan; Jing Zhang; Jin-Shui Zhu
Journal:  Int J Immunopathol Pharmacol       Date:  2020 Jan-Dec       Impact factor: 3.219

Review 3.  The phytochemical and pharmacological profile of taraxasterol.

Authors:  Fengjuan Jiao; Zengyue Tan; Zhonghua Yu; Bojie Zhou; Lingyan Meng; Xinyue Shi
Journal:  Front Pharmacol       Date:  2022-08-04       Impact factor: 5.988

  3 in total

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