R W Gråwe1, S Levander. 1. Department of Psychiatry and Behavioural Medicine, University of Trondheim, Norway.
Abstract
OBJECTIVE: To assess neuropsychological impairments among fairly young schizophrenic patients over time, and relations between impairment and symptoms, drug type and dose. METHOD: Clinical and neuropsychological data for 29 schizophrenic patients have been published earlier. Twenty of these patients were retested after 3 years using the same methods. RESULTS: The patients displayed stable impairments in most neuropsychological tests. Vocabulary and focused attention improved over time, whereas response slowness became more pronounced. Symptoms varied considerably over time. A specific pattern of neuropsychological impairments, but not measures of psychopathology, predicted clinical outcome. Patients were unable to judge their test performance. CONCLUSION: A few years after the first episode, our patients displayed a specific pattern of neuropsychological impairment, which predicted clinical outcome. One aspect of the impairment appears to be failure at self-monitoring.
OBJECTIVE: To assess neuropsychological impairments among fairly young schizophrenicpatients over time, and relations between impairment and symptoms, drug type and dose. METHOD: Clinical and neuropsychological data for 29 schizophrenicpatients have been published earlier. Twenty of these patients were retested after 3 years using the same methods. RESULTS: The patients displayed stable impairments in most neuropsychological tests. Vocabulary and focused attention improved over time, whereas response slowness became more pronounced. Symptoms varied considerably over time. A specific pattern of neuropsychological impairments, but not measures of psychopathology, predicted clinical outcome. Patients were unable to judge their test performance. CONCLUSION: A few years after the first episode, our patients displayed a specific pattern of neuropsychological impairment, which predicted clinical outcome. One aspect of the impairment appears to be failure at self-monitoring.
Authors: Wolfgang Wölwer; Jürgen Brinkmeyer; Mathias Riesbeck; Lena Freimüller; Ansgar Klimke; Michael Wagner; Hans-Jürgen Möller; Stefan Klingberg; Wolfgang Gaebel Journal: Eur Arch Psychiatry Clin Neurosci Date: 2008-11 Impact factor: 5.270
Authors: Paula Calvo; Joan R Fortuny; Sergio Guzmán; Cristina Macías; Jonathan Bowen; María L García; Olivia Orejas; Ferran Molins; Asta Tvarijonaviciute; José J Cerón; Antoni Bulbena; Jaume Fatjó Journal: Front Psychol Date: 2016-05-06